Category Archives: ILRI

A frozen zoo in Nottingham ‘bio-banks’ wildlife threatened with extinction

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HanotteOlivier_08APM

We thought it appropriate in this United Nations ‘International Year of Biodiversity’ to highlight not only work by the International Livestock Research Institute (ILRI) and its partners (see ‘Livestock Diversity Needs Genebanks Too’, an opinion piece by ILRI Director General Carlos SerĂŠ published on the SciDevNet website on 21 May 2010) to conserve breeds and genes of native livestock that are rapidly disappearing, but also those of wild animals similarly threatened.

The Frozen Ark is such an initiative. It is led by Olivier Hanotte, an animal geneticist who spent many years at ILRI working to conserve livestock genetic resources indigenous in developing countries. These days Hanotte is running The Frozen Ark Consortium, a worldwide group of institutions coordinated from an office within a Frozen Ark Unit at the School of Biology at the University of Nottingham in the United Kingdom: Frozen.Ark@nottingham.ac.uk

The aim of the Frozen Ark is to preserve, for hundreds if not thousands of years, critical information about the species collected. As their website explains: ‘Despite the best efforts of conservationists, thousands of extinctions have occurred before the animals could be rescued. There has not been enough knowledge or money to stem the tide. This pattern is being repeated across all animal groups and emphasises the importance of collecting the DNA and cells of endangered animals before they go extinct. The loss of a species destroys the results of millions of years of evolution. If the cells and DNA are preserved, a very great deal of information about the species is saved. . . . For animals endangered but not yet extinct, the stored DNA and cells can also provide renewable resources of variation for revitalising captive breeding populations when the loss of variation through inbreeding threatens their survival.’

What has caught the public’s imagination is the possibility—a possibility ever more credible in light of ongoing, transformative, breakthroughs in molecular biology, particularly genetics and genomics, as well as drastic falls in the cost of sequencing genomes—that in future scientists will be able to reconstruct extinct animals from such preserved material.

‘While the reconstruction of extinct species from frozen material is not yet practicable, the possibility is not remote,’ says Hanotte. ‘If we fail to preserve the DNA and cells, the information and the possibilities will be lost forever. If DNA is stored in liquid nitrogen at -196 degrees Centigrade, it should survive intact for many hundreds, and possibly thousands, of years.’

The International Union of the Conservation of Nature (IUCN) Red List distinguishes more than 16,000 animal species that are under threat. The Fozen Ark aims eventually to collect the DNA of all these species, and the viable cells (somatic cells, eggs, embryos and sperm) of as many as possible, over the next 50 years. But Hanotte is quick to point out that the Frozen Ark Project is not a substitute for conserving the world’s diverse wildlife species, but is rather ‘a practical and timely backup of their genetic material.’

For more information, visit the Frozen Ark Website.

And watch the online version of this week’s broadcast (30 Mar 2010) of the American television program ’60 Minutes’, which explores the possibility of Resurrecting the Extinct from frozen samples.

Livestock goods and bads: Filmed highlights of ILRI’s 2010 Annual Program Meeting

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At the 2010 Annual Program Meeting (APM) of the International Livestock Research Institute (ILRI), held in April in Addis Ababa, Ethiopia, several hundred participants debated and discussed the challenges facing the global livestock industry. ILRI and its partners are investigating ways to promote smallholder participation in livestock markets, more sustainable ways for livestock keepers to use natural resources, and ways to improve livestock pathways out of poverty.

Some of the presentations made during the meeting on the theme of 'Livestock: the Good, the Bad and the Gaps' were captured on film. We share three of those below.

The first film is a presentation by ILRI agricultural systems analyst Mario Herrero on the important place of livestock for smallholder farmers in developing economies. Herrero highlights the many benefits livestock bring to the rural poor and argues that the rapidly expanding sector will need to be better managed and to reduce the environmental risks it poses if it is to continue to be productive. Herrero argues for an integrated assessment of the effects of the global livestock industry on various agro-ecosystems important to the poor.

In the second film, ILRI veterinary and food safety researcher Delia Grace discusses the human health risks associated with livestock keeping. Grace notes that zoonotic diseases (those transmitted between animals and people) and emerging infectious diseases (such as bird flu) are two of the well-known risks associated with livestock. But she says that animals provide a means of regulating diseases because they can serve as sentinels that lets communities and public health officials know of disease outbreaks before the diseases can affect humans. She makes the case for more research to address the many common misconceptions that exist about livestock and human health.

In the third film, Narayan Hedge, of India's BAIF Development Research Foundation, highlights the important role livestock play in providing a livelihood for nearly 700 million people in India. He makes an appeal for better livestock technologies, better infrastructure, and more efficient management of the industry so that more smallholder farmers can use livestock to escape poverty.

Busy in Edinburgh: News from climate and systems scientist Phil Thornton

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Philip Thornton at Climate Meeting in Copenhagen 2009

Philip Thornton, an agricultural systems analyst specializing in climate change and pro-poor livestock research for development issues, has worked for 14 years as a senior scientist and program leader at the Africa-based International Livestock Research Institute (ILRI). For the last 8 years, he has served ILRI as a consultant from his home in Edinburgh.

This year, Thornton was appointed leader of a research theme of a new challenge program of the Consultative Group on International Agricultural Research (CGIAR) called 'Climate Change, Agriculture and Food Security'. This CGIAR challenge program is likely this year to be transformed into one of the CGIAR's new 'mega programs'. His theme is titled 'Diagnosing vulnerability and analyzing opportunities'. Thornton will split his time equally between this new CGIAR climate change initiative and ILRI research on livestock pathways out of poverty.

As reported in the Winter 2009 issue of Agriculture for Development, the Tropical Agriculture Association last year bestowed on Thornton 'Development Agriculturist of the Year' Award 'in recognition of his contribution to international agricultural development through greater understanding of tropical agricultural systems'. The Association highlighted Thornton's prodigious work that has inform policies addressing climate change, land use and poverty alleviation.

In the current, Spring 2010, issue of Agriculture for Development, Thornton has published an article on 'Climate change and livestock keepers in developing countries: What are the prospects?'.  The paper presents examples of possible impacts on livelihoods in sub-Saharan Africa 'of long-term changes in climate, and then of possible impacts of short-term changes in climate variability.' For example, Thornton reports that research indicates that 'there are widespread parts of the continent that are currently classified as mixed crop-livestock rainfed arid-semiarid systems, in which cropping is possible but may well not be in 2050'.

'All in all', writes Thornton, 'the coming decades are likely to see substantial shifts in the patterns of African cropping and livestock keeping.' The paper concludes with a summary of options for dealing with these types of changes in future.

Examples: 'Helping livestock keepers understand and deal with current levels of climate variability can provide one entry point to the problems posed by increasing variability in the future and to the options that may be needed to deal with it. For example, weather information can be used to assist rural communities in managing the risks associated with rainfall variability, and can also feed into livestock insurance schemes that are weather-indexed: policyholders are paid in response to trigger events such as abnormal rainfall or high local animal mortality rates. An index insurance scheme based on satellite imagery is currently being piloted in several areas of drought-prone northern Kenya. It may also be possible for livestock keepers to change the mix of livestock species and/or breeds that they keep, a strategy that has been practised in the past by some pastoralists in East and West Africa, for example. Longer term approaches to adaptation are also needed.'

Thornton is also an Honourary Fellow in the College of Science and Engineering at the University of Edinburgh and Editor-in-Chief of the scientific journal Agricultural Systems.

Gates entry into CGIAR: Will research technologies or innovation systems rule the day?

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GatesBill_Flickr_WorldEconomicForum

In SciDev.Net this week, Yojana Sharma describes what people see as benefits and concerns about the Bill & Melinda Gates Foundation joining the Consultative Group on International Agricultural Research (CGIAR), which supports the International Livestock Research Institute (ILRI) and 14 other centres around the world.

Prabhu Pingali, head of agriculture policy at the Foundation, acknowledges: ‘The big player in this game is obviously CGIAR. . . . The CGIAR has a much broader agenda than we do . . . .' This, says Sharma, 'is a reference to the group’s growing engagement with all aspects of improving agricultural productivity in the developing world.

Andy Hall, a researcher into rural innovation for the United Nations University in Maastricht, in the Netherlands, worries that: ‘The underlying thinking at Gates is that science can solve the problems . . . .  This was the way CGIAR was in the past, and the danger is that Gates is reinventing that approach.’

Sharma concludes that: ‘The critics say that the tensions between those who favour a science- and technology-driven approach to increasing agricultural productivity, and others (such as Hall) who prefer to think in terms of promoting broader agricultural innovation systems, are at their acutest when it comes to genetically modified food.’

Which begs the question as to why so many think that a focus on agricultural technology is incompatible with a focus on agricultural innovation systems. Surely both approaches — interacting in synergy since the dawn of agriculture — are still needed.

http://www.scidev.net/

http://www.merit.unu.edu/

http://www.gatesfoundation.org/

Indian dairy is big dairy – and it’s all done by small producers

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India, Andhra Pradesh, Ramchandrapuram village

A recent article in the Economist — ‘Indian policymakers should see agriculture as a source of growth, not votes’ — in its 13-19 Mar 2010 issue states that: ‘Indian agriculture has performed so poorly largely because governments have treated it as a source of votes rather than as an engine of growth. . . . India’s government still fixes prices and subsidises inputs, when public money would be far better spent on infrastructure and research. . . . India needs to stop seeing agriculture as a problem to be nursed and start thinking of it as an opportunity to be grasped. . . . India is already an agricultural force in some crops. It is the second-biggest exporter of cotton and was a net exporter of cereals for a decade after 1995 . . . .’

What the Economist article omits to mention is that India nearly a decade ago (2001) became the world’s biggest milk producer. Remarkably, almost all of that milk is produced by some 40 million households keeping just a few cows or buffaloes on small plots of land. Those households are, indeed, an opportunity to be realized.

For more information about smallholder dairy research, visit ILRI’s ‘Livestock Markets Digest‘ blog.

Overcoming the Napier grass disease threat to East African dairy farmers

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Also called elephant grass, Napier grass is planted on farms across East Africa as a source of feed for dairy cows. Farmers cut the grass for their livestock, carrying it home for stall feeding.

It is the most important forage grass in the region, constituting 40 to 80% of forages used by smallholder dairy farmers. In Kenya, half a million smallholder dairy producers rely on Napier grass to feed their cows. In Uganda, 90% of farmers rely entirely on Napier grass as fodder for their improved dairy cattle.

The livelihoods of these farmers are threatened by outbreaks of stunt and smut diseases affecting the Napier grass. To tackle the threat, the Association for Strengthening Agricultural Research in Eastern and Central Africa (ASARECA) funded a three-year project to determine the extent of the disease problem, to collect disease-resistant Napier grass clones identified by farmers, and to identify best management practices used by farmers to mitigate the impact of the diseases.

After three years researching the problem in Kenya, Tanzania and Uganda, project researchers from the International Livestock Research Institute, Rothamsted Research, the Kenya Agriculture Research Institute, the National Agricultural Research Organisation (Uganda) and the National Biological Control Programme (Tanzania) will meet with colleagues from the region to share results and recommendations, promote good practices and draw other scientists into the project.

The workshop will be held at ILRI Ethiopia from 1 to 3 June, 2010.

More information:

Project website

Project outputs

Project news item from Kenya

Livestock vaccine offers lifeline to many

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ITM Vaccine

A vaccine is being made available to save the lives of a million cattle in sub-Saharan Africa against a lethal disease and to help safeguard the livelihoods of people who rely on their cattle for their survival.

East Coast fever is a tick-transmitted disease that kills one cow every 30 seconds. It puts the lives of more than 25 million cattle at risk in the 11 countries of sub-Saharan Africa where the disease is now endemic. The disease endangers a further 10 million animals in regions such as southern Sudan, where it has been spreading at a rate of more than 30 kilometres a year. While decimating herds of indigenous cattle, East Coast fever is an even greater threat to improved exotic cattle breeds and is therefore limiting the development of livestock enterprises, particularly dairy, which often depend on higher milk-yielding crossbred cattle. The vaccine could save the affected countries at least a quarter of a million US dollars a year.

Registration of the East Coast fever vaccine is central to its safety and efficacy and to ensuring its sustainable supply through its commercialization. The East Coast fever vaccine has been registered in Tanzania for the first time, a major milestone that will be recognized at a launch event in Arusha, northern Tanzania, on May 20. Recognizing the importance of this development for the millions whose cattle are at risk from the disease, governments, regulators, livestock producers, scientists, veterinarians, intellectual property experts, vaccine distributors and delivery agents as well as livestock keepers – all links in a chain involved in getting the vaccine from laboratory bench into the animal – will be represented.

An experimental vaccine against East Coast fever was first developed more than 30 years ago at the Kenyan Agricultural Research Institute (KARI). Major funding from the UK Government’s Department for International Development (DFID) and others enabled work to produce the vaccine on a larger scale. When stocks from 1990s ran low, the Africa Union/Interafrican Bureau for Animal Resources and chief veterinary officers in the affected countries asked the International Livestock Research Institute (ILRI) to produce more and ILRI subsequently produced a million doses of the vaccine to fill this gap. But the full potential for livestock keepers to benefit from the vaccine will only be achieved through longer term solutions for the sustainable production, distribution and delivery of the vaccine.

With $28US million provided by the Bill & Melinda Gates Foundation and DFID, a not-for-profit organization called GALVmed (Global Alliance for Livestock Veterinary Medicines) is fostering innovative commercial means for the registration, commercial distribution and delivery of this new batch of the vaccine. A focus on sustainability underpins GALVmed’s approach and the Global Alliance is bringing public and private partners together to ensure that the vaccine is available to those who need it most.

Previous control of East Coast fever relied on use of acaracide dips and sprays, but these have several drawbacks. Ticks can develop resistance to acaracides and regular acaricide use can generate health, safety and environmental concerns. Furthermore, dipping facilities are often not operational in remote areas.

This effective East Coast fever vaccine uses an ‘infection-and-treatment method’, so-called because the animals are infected with whole parasites while being treated with antibiotics to stop development of disease. Animals need to be immunized only once in their lives, and calves, which are particularly susceptible to the disease, can be immunized as early as 1 month of age.

Over the past several years, the field logistics involved in mass vaccinations of cattle with the infection-and-treatment method have been greatly improved, due largely to the work of a private company, VetAgro Tanzania Ltd, which has been working with Maasai cattle herders in northern Tanzania. VetAgro has vaccinated more than 500,000 Tanzanian animals against East Coast fever since 1998, with more than 95% of these vaccinations carried out in remote pastoral areas. This vaccination campaign has reduced calf mortality in herds by 95%. In the smallholder dairy sector, vaccination reduced the incidence of East Coast fever by 98%. In addition, most smallholder dairy farmers reduced their acaracide use by at least 75%, which reduced both their financial and environmental costs.

Notes for Editors

What is East Coast fever?
East Coast fever is caused by Theleria parva (an intracellular protozoan parasite), which is transmitted by the brown ear tick Rhipicephalus appendiculatus. The parasites the tick carries make cattle sick, inducing high fever and lympho-proliferative syndrome, usually killing the animals within three weeks of their infection.

East Coast fever was introduced to southern Africa at the beginning of the twentieth century with cattle imported from eastern Africa, where the disease had been endemic for centuries. This introduction caused dramatic cattle losses. The disease since then has persisted in 11 countries in eastern, central and southern Africa – Burundi, Democratic Republic of Congo, Kenya, Malawi, Mozambique, Rwanda, Sudan, Tanzania, Uganda, Zambia and Zimbabwe. The disease devastates the livelihoods of small-scale mixed crop-and-livestock farmers, particularly smallholder and emerging dairy producers, as well as pastoral livestock herders, such as the Maasai in East Africa.

The infection-and-treatment immunization method against East Coast fever was developed by research conducted over three decades by the East African Community and the Kenya Agricultural Research Institute (KARI) at Muguga, Kenya (www.kari.org). Researchers at the International Livestock Research Institute (ILRI), in Nairobi, Kenya (www.ilri.org), helped to refine the live vaccine. This long-term research was funded by the UK Department for International Development (DFID) (www.dfid.gov.uk) and other donors of the Consultative Group on International Agricultural Research (CGIAR) (www.cgiar.org).

The first bulk batch of the vaccine, produced by ILRI 15 years ago, has protected one million animals against East coast fever, with the survival of these animals raising the standards of living for many livestock keepers and their families. Field trials of the new vaccine batch, also produced at ILRI, were completed in accordance with international standards to ensure that it is safe and effective.

How is the vaccine stored and administered?
Straws of the East Coast fever vaccine are stored in liquid nitrogen until needed, with the final preparation made either in an office or in the field. The vaccine must be used within six hours of its reconstitution, with any doses not used discarded. Vaccination is always carried out by trained veterinary personnel working in collaboration with livestock keepers. Only healthy animals are presented for vaccination; a dosage of 30% oxytetracycline antibiotic is injected into an animal’s muscle while the vaccine is injected near the animal’s ear. Every animal vaccinated is given an eartag, the presence of which subsequently increases the market value the animal. Young calves are given a worm treatment to avoid worms interfering with the immunization process.

Note
Case studies illustrating the impact of the infection-and-treatment vaccine on people’s lives are available on the GALVmed website at: www.galvmed.org/path-to-progress
For more information about the GALVmed launch of the live vaccine, on 20 May 2010, in Arusha, Tanzania, go to www.galvmed.org/

Genebanks needed to save farm animal diversity of the South—and assure the world’s future food supply

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Carlos Sere amongst farm animals

Opinion piece in SciDev.net by Carlos Seré, Director General ILRI

Today, scientists are reconstructing the genomes of ancient mastodons, found in the frozen north. Dreams of resurrecting lost species rumble in the collective imagination. At the same time, thousands of still-existing farm animal breeds—nurtured into being by generations of farmers attuned to their environments—are slipping into the abyss of extinction, below the wire of awareness.

Livestock genetic diversity is highly threatened worldwide, but especially in the South, where the vast majority of remaining diversity resides. This diversity—of cattle, goats and sheep, swine and poultry—is as essential to the future world food supply as is the crop diversity now being stored in thousands of collections around the world and in a fail-safe crop genebank buried in the Arctic permafrost. But no comparable effort exists to conserve the animals or the genes of thousands of breeds of livestock, many of which are rapidly dying out.

Hardy and graceful Ankole cattle, raised across much of East and Central Africa, are being replaced by black-and-white Holstein-Friesian dairy cows and could disappear within the next 50 years. In Viet Nam, the percentage of indigenous sows declined from 72 per cent of the total population in 1994 to only 26 per cent just eight years later. In some countries, national chicken populations have changed practically overnight from genetic mixtures of backyard fowl to selected uniform stocks raised under intensive conditions.

Some 20 per cent of the world’s 7,616 breeds of domestic livestock are at risk, according to the Food and Agriculture Organization of the United Nations. And change is accelerating. Holstein-Friesian dairy cows are now raised in 128 countries in all regions of the world, and an astonishing 90 per cent of all cattle in the North are of just six tightly defined breeds.

Most endangered livestock breeds are in developing countries, where they are herded by pastoralists or tended by farmers who grow both crops and livestock on small plots of land. With survival a day-to-day issue for many of these small-scale farmers, they are unlikely to make conservation of their rare breeds a priority, at least not without significant assistance. From Africa to Asia, farmers of the South, like the farmers of Europe, Oceania and the Americas before them, are increasingly choosing the breeds that will produce more milk, meat and eggs to feed their hungry families and raise their incomes.

They should be supported in doing so. At the same time, the breeds that are being left behind not only have intrinsic value, but also may possess genetic attributes critical to addressing future food security challenges, in developed or developing countries, as the climate, pests and diseases all change. Policy support for their conservation is needed now. This support could be in the form of incentives that encourage farmers to keep traditional animals. For example, policies could support breeding programs that increase the productivity of local breeds, or they could facilitate farmers’ access to niche markets for traditional livestock products. And policymakers should take the value of indigenous breeds into account when designing restocking programs following droughts, disease epidemics, civil conflicts or other disasters that deplete animal herds.

But even such assistance will not enable developing-world farmers to stem all the losses of developing-world farm animals. A parallel, even bigger, effort, linking local, national and international resources, must be launched to conserve livestock genetic diversity by putting some of it ‘in the bank’. The cells, semen and DNA of endangered livestock should be conserved—frozen—and kept alive. The technology is available and has been used for years to aid both human and animal reproduction. It should also be used to conserve the legacy of 10,000 years of animal husbandry. Furthermore, such collections must be accompanied by comprehensive descriptions of the animals and the populations from which they were obtained and the environments under which they were raised.

We should know the type of milking goat that is able to bounce back quickly from a drought. We should know the breeds of cow that resist infection with the animal form of sleeping sickness. We should know the native chickens that can survive avian flu.

We should do all we can to assist farmers and herders in the conservation of these endangered animals—especially now, in the midst of rapid agricultural development. And if some of these treasured breeds fail to survive the coming decades of change, we should at least have faithfully stored and recorded their presence, and have preserved their genes. It is these genes that will help us keep all our options open as we look for ways to feed humanity and to cope with coming, yet unforeseen, crises.

Kenya's Maasai herders take jobs and farm crops to cope with change

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Collaborative research between Kenyan Maasai communities and a researcher from Canada’s McGill University has identified how these semi-nomadic herding communities are changing to cope with changing climate and land tenure systems. Results of research conducted during a great drought in Kenya’s Maasailand and other regions from 2007 to 2009 show that more and more Maasai households are diversifying their livelihoods and making use of ‘strategic mobility’ to cope with changing land tenure systems.
In a presentation last week of research findings at the International Livestock Research Institute (ILRI) campus, in Nairobi, Kenya, John Galaty, of McGill University, noted that ‘the Maasai community is dealing with the aftermath of the long drought, which devastated their livelihoods, by making more opportunistic use of their land, by diversifying into cropping, by keeping fewer and faster growing animals and by taking on paying jobs.’
In studies done across nine sites in Ole Tepesi, Maji Moto and Elangata Wuas in Kenya’s Kajiado and Narok districts, researchers found that members of the communities who diversified into agriculture had higher chances of maintaining their livelihoods during droughts than those who relied on animals alone. The research looked at the experiences of higher, medium- and low-income households.
Well-known methods used by the Maasai to cope with drought—such as splitting herds, keeping fewer animals and moving stock to find water or grass—are still in use. A closer assessment of mobility patterns showed that pastoralists with external sources of income could afford to keep their animals in one location during drought because they were able to buy and bring in feed and drugs for them. The poorest members of the community were hurt the most by drought because they were forced to move their animals in search of fodder or water. The study also disclosed that the richer members of the community hired their poorer neighbours to herd their animal stock to better grazing lands while they themselves pursued other livelihood options.
Galaty said that the movement of animals by the Maasai is never haphazard. ‘The Maasai just don’t start to move once the drought bites,’ he said. ‘We found out that most people moved their animals based on social relationships. People were linked to relatives or friends who lived in areas where pasture was still available. Others relied on word from other parts of the region that pasture was available before starting to move. In such cases, conventional boundaries were not enforced and people openly shared “private” resources. Some even moved their animals into Tanzania, where they were welcomed by the Maasai who live there.’ The research also showed that stock movement by members of Maasai group ranches was also well planned and coordinated.
Nonetheless, the increasingly popular subdivision of Maasai communal lands into private holdings, often with little consultation with the communities concerned, is greatly restricting the traditional mobility of these herding communities. Individuals are increasingly enforcing their rights to private ownership, and use, of land in both Kajiado and Narok districts. Such privatization of land threatens Maasai pastoralism by disrupting the well-established ‘mobility’ mechanism they use to cope with periodic drought.
An earlier (not yet published) study by David Nkedianye, a Maasai graduate student with ILRI, on the effects of the 2005 to 2006 drought on Kenyan Maasai indicates that land privatization and large movements of animals can weaken the ability of households to cope with drought. For example, at times in this drought the Kitengela Maasai rangeland, although it received relatively good rainfall, had the greatest number of livestock deaths because of an influx of livestock brought to Kitengela by herders from other Maasai communities in southern Kenya and northern Tanzania.

Staff of ILRI’s People, Livestock and Environment Theme, who are conducting livestock research in these same Maasai lands, hosted Galaty and organized for his presentation.









US$4.4 million awarded for research to build a climate model able to predict outbreaks of infectious disease in Africa

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Cow suffering from trypanosomosis

Scientists at the University of Liverpool, in the UK, and the International Livestock Research Institute (ILRI), in Kenya, are working with 11 other African and European partners on a US$4.4-million (UKÂŁ3 million-) project to develop climate-based models that will help predict the outbreak and spread of infectious diseases in Africa.

The researchers are working to integrate data from climate modelling and disease-forecasting systems so that the model can predict, six months in advance, the likelihood of an epidemic striking. The research, funded by the European Commission Seventh Framework, is being conducted in Ghana, Malawi and Senegal. It aims to give decision-makers the time needed to deploy intervention methods to stop large-scale spread of diseases such as Rift Valley fever and malaria, both of which are transmitted by mosquitoes.

It is thought that climate change will change global disease distributions, and although scientists know a lot about the climate triggers for some diseases, they don’t know much about how far into the future these disease events can be predicted. This new project brings together experts to investigate the links between climate and vector-borne diseases, including ‘zoonotic’ diseases, which are transmissible between animals and humans.

ILRI veterinary researcher Delia Grace says that diseases shared by people and animals are under-investigated although they are critically important for public health. ‘Fully 60% of all human diseases, and 75% of emerging diseases such as bird flu, are transmitted between animals and people,’ she said.

ILRI geneticist Steve Kemp said that the project is making use of ILRI’s advanced genomics capacities to analyse pathogens from the field and to integrate the data collected on both pathogen distribution and climatic factors. ‘From ILRI’s point of view,’ Kemp said, ‘this project is particularly exciting because it brings strong climate and weather expertise that complements systems recently built by ILRI and its partners to detect outbreaks of Rift Valley fever and to determine its spread.’

The new project also complements ILRI’s ongoing work to better control trypansomosis in West African livestock, a disease transmitted by tsetse flies. Trypanosomosis, which is related to sleeping sickness in humans, causes devastating losses of animals—along with animal milk, meat, manure, traction and other benefits—across a swath Africa as big as continental USA. Members of the new modeling project will conduct research in some of the same locations as ILRI’s West African trypanosomosis project, Kemp explained, and work with some of the same partner organizations, which should generate synergies that benefit both projects.

The risk of epidemics in tropical countries increases shortly after a season of good rainfall—when heat and humidity allow insects, such as mosquitoes, to thrive and spread diseases. Matthew Baylis, from Liverpool’s School of Veterinary Science, explained how this works with Rift Valley fever: ‘Rift Valley fever can spread amongst the human and animal population during periods of heavy rain, when floodwater mosquitoes flourish and lay their eggs. If this rainfall occurs unexpectedly during the dry season, when cattle are kept in the villages rather than out on the land, the mosquitoes can infect the animals at the drinking ponds. Humans can then contract the disease by eating infected animals. Working with partners in Africa, we can bring this information together to build a much more accurate picture of when to expect epidemics.

Andy Morse, from Liverpool’s School of Environmental Sciences, said the project combines historical and contemporary climate data with disease incidence information, including that for vector-borne diseases, as well as integrating monthly and seasonal forecasts. The resulting single, seamless, forecast system, Morse said, should allow projections of disease risk to be made beyond the conventional predictable time limit. ‘All this information will be fed into a decision-support system to be developed with decision-makers on national health issues’ in the three target countries.

The project was launched at a conference at the University of Liverpool on 19 April 2010.

For more information, contact ILRI scientist Steve Kemp. ILRI email contacts are formatted as follows: f.surname@cgiar.org: replace ‘f’ with the staff member’s first initial and replace ‘surname’ with the staff member’s surname.

The 13 research partners:
Abdus Salam International Centre for Theoretical Physics (Italy), Centre de Suivi Ecologique (Senegal), Consejo Superior de Investigaciones Cientificas (Spain), European Centre for Medium-Range Weather Forecasts (UK), Fundació Privada Institut Català de Ciències del Clima (Spain), Institut Pasteur de Dakar (Senegal), International Livestock Research Institute (Kenya), Kwame Nkrumah University of Science and Technology (Ghana), Universitaet zu Koeln (Germany), University Cheikh Anta Diop de Dakar (Senegal), University of Liverpool (UK), University of Malawi (Polytechnic & College of Medicine), University of Pretoria (South Africa)

Biologists in Nairobi to take part in two new animal health projects announced this week by the US National Science and Gates foundations

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East Coast Fever

The National Science Foundation (NSF) of the United States announced on 12 May 2010 that the Foundation, in partnership with the Bill & Melinda Gates Foundation, is awarding 15 grants worth US$20 million in support of basic research for generating sustainable solutions to big agricultural problems in developing countries.

These are the first grants in a new five-year Basic Research to Enable Agricultural Development (BREAD) program, which is jointly funded by NSF and the Gates Foundation.

The awards in this first year of funding will allow leading scientists worldwide to work together in basic research testing novel and creative approaches to reducing longstanding problems faced by smallholder farmers in poor countries.

Scientists from the Nairobi, Kenya, animal health laboratories of the International Livestock Research Institute (ILRI) will participate in 2 of the 15 projects selected among the many submitted to BREAD for funding.

Biologists at New York and Michigan State universities and Regeneron Pharmaceuticals (USA), the Roslin Institute and the University of Edinburgh (UK) and ILRI (Kenya) will test a novel approach to developing cattle that are resistant to trypanosomosis, a deadly cattle disease that is closely related to sleeping sickness in humans and that holds back animal agriculture across a swath of Africa as large as continental USA.

In another project, scientists from the University of Vermont and Plum Island Animal Disease Center (USA) will work with the University of Copenhagen (Denmark) and ILRI on use of advanced genetics to develop vaccines for East Coast fever and other cattle diseases that threaten the livelihoods of millions of smallholder farmers in sub-Saharan Africa.

Go here for a 12 May 2010 news release from the US National Science Foundation: http://www.nsf.gov/news/news_summ.jsp?cntn_id=116932

A complete list of 2010 BREAD awards can be accessed at: http://www.nsf.gov/bio/pubs/awards/bread10.htm

Climate experts gather in Nairobi to seek ‘transformative’ solutions for feeding a growing and warming world

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Achim Steiner making his introductory remarks at the CCAFS conference

The livelihoods of many of the world’s rural poor are increasingly threatened by climate change. Most of these livelihoods are dependent on farming, fishing and forests. Climate change will affect and worsen the living conditions of people who are already vulnerable and food insecure, especially in developing countries. In the face of what seems an inevitable change, scientists are looking for solutions that will help poor smallholder farmers adapt their agricultural practices to cope with, and mitigate, climate change.

Through a new Climate Change Agriculture and Food Security (CCAFS) initiative, a consortium of the Consultative Group on International Agricultural Research (CGIAR) is seeking innovative approaches to address the emerging threats to global agriculture and food security. CCAFS is a 10-year initiative launched by the CGIAR and the Earth System Science Partnership (ESSP). CCAFS works to diagnose and analyse threats to agriculture and food security, to provide evidence for development of climate change policies and to identify and develop pro-poor adaptation and mitigation practices that will benefit poor farmers and urbanites alike.

In a CCAFS workshop held at the World Agroforesty Centre (ICRAF), in Nairobi, Kenya, on 4 May 2010, scientists and researchers held discussions on ways of ‘building food security in the face of climate change’. Among the key challenges to food security identified by the participants were: lack of a platform by which developing countries could share their experiences in dealing with climate change; weaknesses in presenting lessons from climate change impacts on farming; and inability to implement policies to address climatic risks to developing-country agriculture because of widespread poverty, limited human capital, and poor governance in many poor countries.

According to Achim Steiner, the Executive Director of the United Nations Environment Program (UNEP), ‘Agriculture needs to be understood within the greater context of livelihood sustainability’. Steiner believes the threat of climate change offers opportunities for agricultural development if new innovative ways of enhancing agriculture are explored. For example, agricultural practices that help communities reduce carbon emissions should be considered. ‘If we can demonstrate that a farming or production system reduces emissions, communities could be paid to develop it for expansion to solve two challenges at the same time. ‘The future of agriculture is not just in increasing production,’ the UNEP head said, ‘but in having working systems that protect the planet and that benefit those who engage in practices that protect the planet and livelihoods of the poor.

Thomas Rosswall, who chairs the CCAFS Steering Committee, noted that the ‘big disconnect [in addressing agricultural production] has been because development and global change have been addressed, researched and funded as unrelated issues’. He said ‘the approach to research needs to change so that it can link the local experiences to global needs while working with the poor to improve agricultural productivity.

Participants of the meeting agreed that ‘transformative solutions’ are needed to address agricultural challenges in the world. These solutions, they agreed, need to work with, not against, nature and they need to address conflicts of interest among farmers, countries and markets. Researchers, they said, need to focus on plant breeding and improving soil fertility. And regional decision-makers need to integrate development and climate-based polices and strategies between countries. In many countries, agricultural productivity is already being linked to climate change. In Africa, for example, an African Bio-Carbon Initiative is working to reduce the impacts of climate change on the continent’s farmers while increasing and sustaining their agricultural production. In India, environmental studies show that climate change is creating opportunities for farmers to increase their vegetable production, and thus their incomes.

According to David Radcliffe, of the European Commission, the CCAFS initiative will build understanding of the problems climate change is causing smallholder tropical farmers and will provide evidence for policies that can reduce these problems. CCAFS will focus on climate hotspots. It will pilot methods to help farmers both adapt to climate change and reduce their production of greenhouse gases, which cause climate change. Both adaptation and mitigation methods, Radcliffe said, will be needed to feed the world’s growing population while using fewer resources.