World’s largest agricultural research partnership, serving 1 billion poor, marks $1 billion funding milestone–CGIAR

Posted on December 18, 2013 by Susan MacMillan

Tanzanian Maasai help vaccinate their calves against lethal East Coast fever (photo credit: ILRI/Stevie Mann).

CGIAR has doubled its funding in the last five years, from $500 million (in 2008) to $1 billion (in 2013).

Officials say harvesting the fruits of this historic commitment could, among other benefits, lift 150 million people in Asia out of poverty by boosting rice production, provide 12 million African households with sustainable irrigation, save 1.7 million hectares of forest from destruction, give 50 million poor people access to highly nutritious food crops, and save up to 1 million cattle from dying untimely deaths each year due to a lethal disease.

The International Livestock Research Institute (ILRI) is one of 15 global research centres belonging to CGIAR, which works with hundreds of partners to develop innovative solutions, tools, and technologies for the benefit of the world’s poorest people. It seeks to bring cutting edge science to bear on a wide range of issues facing millions of farmers and other poor smallholders in developing countries who collectively generate nearly 70 percent of the world’s food production.

‘The $1 billion in funding will help finance CGIAR’s 16 global research programs and accelerate the development of scientific, policy and technological advances needed to overcome complex challenges—such as climate change, water scarcity, land degradation, and chronic malnutrition, greatly improving the well-being of millions of poor families across the developing world’, said Frank Rijsberman, CEO of the CGIAR Consortium.

For more than 40 years, CGIAR and its partners have transformed the lives of hundreds of millions of people with the tangible outcomes of agriculture research, including improved crop varieties, sustainable farming methods, new fish strains, novel livestock vaccines, climate-smart solutions, and incisive policy analysis.

For example:

In eastern Africa, a ‘live’ vaccine against the deadly cattle disease East Coast fever developed by ILRI with the Kenya Agricultural Research Institute and other partners and now being distributed by GALVmed, has saved 620,000 calves, benefiting up to 50,000 poor households that rely on cattle for food and income. The vaccine could benefit 20 million more people in the region, with annual benefits of $270 million.

Drought tolerant maize has increased farmers’ yields by 20-30%, benefiting 20 million people in 13 African countries.
‘Scuba rice’, which can survive under water for two weeks, is protecting the harvests, incomes, and food security of poor farmers and consumers across monsoon Asia.
Newly developed potato varieties that withstand late blight disease and yielded eight times more than native varieties in the region have made the difference between having enough to eat or not in the Paucartambo province of Peru, where late blight threatened to devastate staple food supplies.
By integrating food crops with trees that draw nitrogen from the air and transfer it to the soil, an innovative agroforestry practice captures carbon and reduces greenhouse gas emissions, while improving soil fertility, rainwater use efficiency, and yields by up to 400% for maize in the Sahel region.
Across Afghanistan, Bangladesh, Ethiopia, Egypt, Nepal, and Pakistan, high-yielding wheat varieties resistant to Ug99, a highly virulent disease, have protected the livelihoods and food security of 500,000 farming families.

Read the CGIAR press release: CGIAR doubles funding to $1 billion in five years, 17 Dec 2013.

ILRI’s Jimmy Smith on global health and food security: Why developing-country livestock matter so much

Posted on October 17, 2013 by Susan MacMillan

Jimmy Smith, director general of the International Livestock Research Institute (ILRI) gave a keynote presentation this morning (17 Oct 2013) at the opening of the Global Animal Health Conference, ‘Developing global animal health products to support food security and sustainability’, in Arlington, Virginia.

Smith began his presentation, ‘Global health and sustainable food security: Why the livestock sectors of developing countries matter’, by setting out the state of global food security and questioning how the world will manage to feed itself as the human population grows before stabilizing at about mid-century. Some 60% more food than is produced now will be needed by then, he said. And, somehow, some 75% of that increase will have to come from increases in productivity rather than from increases in land under cultivation. This higher production, he said, must be achieved while at the same time reducing poverty and hunger and addressing environmental, social and health concerns. In addition, the greater food production will have to be achieved in the face of temperatures 2−4 degrees C warmer than today’s.

He pointed out the great nutritional divides in today’s world, and warned of malnutrition’s huge financial as well as public health costs.

He noted that gains in consumption of meat in poor and emerging economies are greatly outpacing those of the industrialized countries.

Smith then pointed out how much of the world’s food comes not from large-scale farmers but rather from hundreds of millions of very small-scale farmers in developing countries.

These small-scale food producers, he said, are more competitive than most people think. He cited two examples. In East Africa, one million smallholders keep Africa’s largest dairy herd, Ugandans produce milk at the lowest cost in the world, and Kenya’s small- and large-scale poultry and diary producers have the same levels of efficiency and profits. In Vietnam, 50% of the country’s pig production is done by farmers with less than 100 pigs, and producers keeping just 1 or 2 sows have lower unit costs than those with more than 4 sows. Scientists estimate that Vietnam’s industrial pig production could grow to meet no more than 12% of the national pig supply in the next 10 years, so small-scale farmers will continue to supply most of the country’s pork for the foreseeable future.

In a series of graphs, ILRI’s director general presented figures for livestock commodities being global leaders, for the huge global trade in livestock products and for the fast-rising demand for meat, milk and eggs in developing countries.

Smith said that the developing world’s smallholder livestock producers can continue to produce most of the world’s milk, meat and eggs only if we can find ways to improve livestock health, especially by reducing food safety problems that reduce market participation by smallholders, by reducing the endemic livestock diseases that greatly lower livestock productivity in developing countries, and by lowering zoonotic disease transmissions that threaten small-scale livestock production in poor countries—as well as human health in all countries.

Food safety in developing countries, where most milk, meat and eggs are sold in informal or ‘wet’ markets, is a bigger problem than most people recognize, the ILRI director general said. He said we need to manage the risks of illness while retaining the benefits—to livelihoods and food and nutritional security—of informally sold livestock foods. And, he said, we have to educate people about the various risks of these informal markets, where common perceptions can be misleading; eating vegetables sold in these markets, for example, can be as risky to health as handling cattle or drinking raw milk.

Gender is an important determinant of food safety in developing countries, Smith said, with evidence indicating that Africa’s women butchers sell safer meat than their male counterparts. Women and children and farm workers are also at greater risking in contracting food-borne diseases.

Regarding health advice, Smith argued that it is most useful when it is tailored for specific circumstances, when it is based on evidence, and when it is developed in and with local communities. It’s also been found that what works best for increasing food safety are social incentives (e.g., ‘good parents do X rather than Y with their milk cows’), and risk- rather than rule-based approaches. Finally, he said, relatively simple and cheap interventions can lead to substantial improvements in food safety.

The big livestock productivity gaps between rich and poor countries, Smith explained, are due largely to poor animal health in these countries.

Livestock diseases take a huge toll . . .

. . . especially in Africa.

And the toll from ‘zoonotic’ diseases, which are transmitted from animals to people, is especially devastating.

These zoonotic infections harm poor people the most.

Incidences of zoonotic events are worringly on the increase . . .

. . . and can have enormous costs . . .

. . . as they spread, just as African swine fever is now spreading.

The animal health markets in developing countries are already significant and are growing rapidly. The global animal health market is a multi-billion-dollar industry. The global human health market amounts to US$1000 million and the global animal health market, including livestock, pets and other animals, some $20 billion. The global livestock health market is worth about $13 billion, with the livestock health market in Africa now experiencing a 15.7% year-on-year growth (the second fastest growth after Latin America).

Just 15 countries make up more than 85% of the global animal health market today; demand for animal health markets in developing and emerging economies is increasingly important.

Take India, for example.

To take advantage of the increasing opportunities in developing countries will require an understanding of smallholder livestock systems and customers, who will need tailored packaging and marketing (e.g., drugs in small packets), delivery systems appropriate for widely dispersed farms, surveillance systems for development of drug resistance, and ‘One Health’ approaches and ‘Rational Drug Use’ used for both people and their animals. Among the ‘game-changing’ livestock health products urgently needed in poor countries and communities are appropriate vaccines for Newcastle disease in poultry and East Coast fever in cattle and quality assurance for all veterinary medicines.

Jimmy Smith ended his presentation with four key messages:

And he closed his presentation the following thoughts.

The risks of ignoring pressing animal health issues in the developing world are huge:

Lost livelihoods in poor countries
Greater global food insecurity
Increased risk of human illness in all countries

The opportunities for improving animal health in developing countries are just as big. With appropriate approaches, this significant animal health market should grow rapidly, for the good of all.

View the presentation.

See other recent presentations by Jimmy Smith:

Improving the environmental sustainability of livestock systems in the developing world–ILRI’s Jimmy Smith, 30 Sep 2013

Why the world’s small-scale livestock farms matter so much: Keynote address at International Grasslands Congress, Part 1, 16 Sep 2013

Why tackling partial truths about livestock matters so much: Keynote address at International Grasslands Congress, Part 2, 16 Sep 2013

Scissors and crazy glue: Lorne Babiuk, award-winning vaccine evangelist, speaks his (clear) mind in Ottawa

Posted on October 9, 2013 by Susan MacMillan

Director of ILRI’s vaccine development program Vish Nene (left) with Canadian vaccinologist and ILRI board member Lorne Babiuk (right) at morning tea with ILRI staff (photo credit: ILRI/Susan MacMillan).

Canadian Lorne Babiuk, an internationally recognized leader in vaccine research, visited the International Development Research Centre (IDRC) in Ottawa yesterday (8 Oct 2013) to deliver a live webcast talk on exciting breakthroughs in the development of animal vaccines, which, he argued, can both improve global food security and reduce the global impacts of infectious diseases.

Babiuk is vice-president of research at the University of Alberta and the recipient of two recent distinguished awards for his outstanding career in vaccinology — the Gairdner Wightman Award in 2012 and the Killam Prize in Health Sciences in 2013. He serves on the board of trustees of the International Livestock Research Institute (ILRI).

For all his illustrious awards, Babiuk talked not like a scientist but rather like ‘a regular guy’, preferring to speak of ‘scissors’ and ‘crazy glue’ to describe molecular advances in vaccinology rather than use scientific jargon.

Here’s some of what he said.

ON POVERTY
One billion people go to bed hungry every night. Not hungry like you and me when we miss a meal. But hungry, really hungry, every day, day in and day out. By 2050, we’ll have another 2 billion people to feed. The last time I checked, they were not making more land. So we’re going to have to do more with the land (and livestock) that we have. We have an opportunity to develop new approaches to increase food supplies or to have a lot more hungry people.

The developing world is looking for more and more protein; those of us in the developed world should not deny them that.

Livestock are a critical component of smallholder farming, which supports about two billion people, some two-thirds of them women

ON DISEASE
I’ve spent my career in infectious diseases. They matter partly because they cost so much. Alberta has still not recovered from BSE. And SARS cost a staggering USD100 billion—USD2 billion in Ontario alone.

Some 74% of new or emerging diseases are ‘zoonotic’, which means they’re transmitted from animals to humans, or from humans to animals. The economic impacts of zoonoses are huge for farmers, for producers, for international traders . . .

ON DISEASES OF THE DEVELOPING WORLD
I have concerns about Rift Valley fever spreading to North America. The West Nile virus, which has the same kind of vector, has already arrived here.

ON BIOTECH
Technology and biotechnology can be a saviour, but it’s a challenge because we have a large number of people against genetically modified food. We have to work with social scientists to make sure we have healthy animals for healthy people

ON RESEARCH
Basic research and applied research are two sides of the same coin—the two of them need each other.
We no longer train our biologists in broad biology but rather in narrower molecular biology studies. That’s a mistake.
We biological scientists must get smarter at engaging social science and scientists.

ON VACCINES
Vaccination has saved more lives than all other treatments and prophylactics combined.
The traditional types of vaccines, live or killed, have given way to really interesting new types.
We eradicated smallpox with a vaccine; that research would never be approved today because the vaccine has too many side effects.
What can we do to change perceptions of vaccines and biotechnology?
It costs something in the order of one billion dollars to get a vaccine approved.

ON VACCINES FOR THE DEVELOPING WORLD
The major obstacle in Africa is to get a commercial company to invest in the regulatory component of a vaccine because there isn’t a financial incentive. You can’t sell a livestock vaccine for much more then 50 cents per dose in a developing countries. That’s why we have to work with African or Asian vaccine companies, which can produce vaccines much cheaper than industrial countries can.

Several diseases in the developing world are protozoan and those are, of course, much bigger challenges. But there have been new donors for protozoan vaccine research. We need to convince more donors that this research is needed.

ON THE ANTI-VACCINE LOBBY
I’m an evangelist for vaccination because I think we have lost the battle to the anti-vaccine lobby. In North Amercia there is a huge anti-tech group. They misquote or use data to push their own agenda at the expense of large numbers of lives lost. Look at the article published decades ago about a possible link between vaccination and autism. Despite decades of subsequent research showing no such links, we still haven’t managed to convince a lot of people that vaccines do not cause autism.

How do we encourage the scientific community to stand up and be more vocal about what they know? We have to continue to advocate and demonstrate what we can do using the new technology. We should promise less and deliver more. We have been our own worst enemies. We have to be realists and say what can be done in what time period. That will give us back some credibility.

People go into science because they like doing the science part of it. If they loved the podium, they would have gone into the social sciences. We need to encourage others to do this kind of communication.

ON TEAM DYNAMICS
Any successful researcher has to stimulate the team around him or her and make them all feel part of something big. Getting people excited about working together as a team, providing a vision, and saying how the team can achieve something, that’s what I’m good at. Get people passionate about something and get them to know it’s their idea. I’m a facilitator. I don’t tell people what to do. I create an environment that facilitates what they do. You have to accept different cultures, different ways of doing science. You have to have patience and go with the flow. I learned patience.

ON HIS SUCCESSFUL CAREER
I still get up in the morning and put one leg in my pants and then the other, just like everyone else.

About CIFSRF
Lorne Babiuk manages a grant funded by the Canadian International Food Security Research Fund (CIFSRF), among others. CIFSRF is a CA$124.5-million program of IDRC undertaken with financial support from the Government of Canada. CIFSRF supports applied research partnerships between Canadian and developing-country organizations to find lasting solutions to hunger and food insecurity. It is a core element of Canada’s Food Security Strategy.

For more information, see the IDRC website.

‘Not by food alone’: Livestock research should be used to make a bigger difference, say African experts

Posted on July 17, 2013 by Susan MacMillan

Livestock matter to the livelihoods and ambitions of most people living in Africa and other developing regions of the world (image credit: ILRI/Rob O’Meara).

Note: This post was developed by ILRI corporate communications staff Paul Karaimu and Muthoni Njiru.

The 6^th Africa Agriculture Science Week (AASW6) of the Forum for Agricultural Research in Africa (FARA) is being held this week (15–Jul 2013) in Accra, Ghana. The official opening and plenary sessions start tomorrow, Thu 18 Jul.

Speaking at Monday’s launch of the whole AASW6 week, Tiemoko Yo, chairperson of FARA, said the science week aimed to respond to some of the burning issues in African agricultural research for development. Many if not most of those issues were discussed in more than 50 side events held over the first 2 days of the week, many of them by CGIAR centres.

One such side event organized by the International Livestock Research (ILRI) explored the role of ‘Livestock research for Africa’s food security and poverty reduction’. Sixty-five people from agricultural and livestock development, extension and government agencies participated in this three-hour session facilitated by ILRI’s Even Le Borgne and held on 15 Jul. Five topics were discussed:

The biomass crisis in intensifying smallholder livestock systems
Vulnerability and risk in drylands
Food safety and aflatoxins
Livestock vaccine biosciences
Mobilizing biosciences for a food-secure Africa

The session started with a look at Africa’s livestock sector as a whole.
After ILRI director Jimmy Smith welcomed the guests to ILRI’s morning discussion, Shirley Tarawali, ILRI director of institutional planning and partnerships, explained one of the aims of the session. ‘Today, with our partners and stakeholders, we’d like to reflect on where we can work closely with others to influence and develop capacity to enhance Africa’s agriculture.’

Half of the highest-value African commodities are livestock products, including milk and meat.—Shirley Tarawali, ILRI

Next was a brief look at an emerging ‘biomass crisis’ in African agriculture.
Iain Wright, who leads an Animal Science for Sustainable Productivity program at ILRI, said ‘Livestock feed is at the interface of the positive and negative effects of livestock raising. Helping Africa’s many millions of farmers and herders to boost their livestock productivity through more and better feeds while also helping them to conserve their natural resources is a major challenge for livestock scientists.’

Biomass production is the most significant user of land resources and water in livestock production systems. We need to think how to produce this biomass more efficiently.—Iain Wright, ILRI

Next up was a quick overview of the public health threats posed by livestock foods and aflatoxins.
‘Ensuring food safety is one of the most important issues facing the agricultural sector today’, said Delia Grace, a veterinary epidemiologist and food safety expert at ILRI. ‘This is especially so in developing countries, where food-borne diseases are among the top five health burdens. Livestock diseases and unsafe milk, meat and eggs pose multiple burdens on the poor. They sicken and kill people and animals and burden national economies with huge economic losses’.

Each year, Africa loses billions of dollars due to aflatoxins, which occur on mouldy maize, groundnuts and other crops and crop harvests. The widespread presence of aflatoxins in Africa hurts the continent not only by making people ill but also by contributing to lost market opportunities.—Delia Grace, ILRI

Unfortunately, she said, efforts to improve food safety standards can end up hurting the poor, who, finding it difficult to meet those standards, are often cut off from the informal markets they depend on. Livestock foods also pose problems, she said.

The most nutritious foods—milk, meat, fish and vegetables—are also the most dangerous. These foods are also among the highest-value agricultural products in terms of generating cash incomes and are especially critical for the well-being of Africa’s women.—Delia Grace, ILRI

Next was an introduction to livestock vaccines for African livestock.
Suzanne Bertrand, deputy director general biosciences at ILRI, reported on ILRI and partner research to produce vaccines that protect African livestock against disease. ‘We want to simplify vaccine production and to understand how the pathogens that are causing African livestock diseases are developing resistance to the drugs used to treat the diseases.’

We want to work on these issues with the immunology and health departments of African universities.—Suzanne Bertrand, ILRI

ILRI scientist Polly Ericksen also spoke on ILRI-partner approaches to new research on pastoral systems in Africa’s drylands and Ethel Makila introduced the state-of-the art facilities and training opportunities in the Biosciences eastern and central Africa-ILRI Hub, endorsed by the New Partnership for Africa’s Development (NEPAD) Comprehensive African Agricultural Development Programme (CAADP) and located in Nairobi, Kenya. ILRI deputy director for research in integrated sciences, John McIntire, provided a synthesis of the morning’s discussions.

From the participants

In agriculture, the livestock sub-sector has been neglected. To meet the Millennium Development Goal of helping people rise out of poverty, we must invest more in smallholder livestock production.—Yusuf Abubakar, executive secretary of the Agricultural Research Council of Nigeria

‘When a research-based agricultural intervention is introduced to a community,’ said Mkhunjulelwa Ndlovu, of Zimbabwe’s Department of Agricultural, Technical and Extension Services, ‘it must be integrated into existing work and involve other stakeholders in development, especially governments, to ensure that use of the intervention is sustained over the longer term.

‘And remember’, Ndlovu said, ‘that the most active members in most communities are women; our interventions must suit their needs.’

We don’t feed ourselves and others with food alone; we also feed ourselves and others in intellectual ways. Capacity is key to driving innovation and change within societies; to build that capacity, we need to change people’s mindsets.—Mkhunjulelwa Ndlovu, Zimbabwe Department of Agricultural, Technical and Extension Services

Group discussions at the ILRI side event on 15 Jul at the 6th Africa Agriculture Science Week (AASW6), in Accra, Ghana, 15-20 Jul 2013, organized by the Forum for Agricultural Research in Africa (FARA) photo credit: ILRI/Ewen Le Borgne).

Recommendations
Those participating in this ILRI-hosted side session agreed on the need for livestock scientists to work in multidisciplinary teams and engage in ‘holistic’ research. Only by doing so, they said, would livestock scientists be in position to evaluate all components affecting the livestock sector and thus to help reduce the many risks and burdens faced by Africa’s millions of small-scale livestock producers.

The participants also agreed that it is the responsibility of livestock and other agricultural researchers to provide policymakers with evidence of how each component of smallholder farming links to others and how investing in one component can make a difference to the other components. Improving animal health, for example, can also improve the safety and nutritional value of animal-source foods.

Recommendations put forward at ILRI’s side meeting for enhancing the livestock sector’s contributions to Africa’s food security and poverty reduction include the following.

Ensure development of high-quality vaccines is supported by high-quality vaccination campaigns that involve local communities.
Incorporate indigenous knowledge to ensure research understands community realities and addresses community needs.
Boost the essential roles of continental and sub-regional approaches to development in the livestock research agendas.

AASW6
FARA’s 6th Africa Agriculture Science Week (AASW6), in Accra, Ghana, includes marketplace exhibitions (15–20 Jul 2013), side events on sub-themes (15–16), a ministerial roundtable alongside a Ghana Day (17 Jul), plenary sessions (18–19) and a FARA Business Meeting (20 Jul). Follow the discussions on Twitter with the hashtag #AASW6 or visit the FARA AASW6 blog.

View all of the ILRI slide presentations: Livestock research for food security and poverty reduction, 15 Jul 2013.

‘Livestock Research for Africa’s Food Security’: Join us at our side event at FARA’s AASW in Accra, 15 July

Posted on July 9, 2013 by Susan MacMillan

Next week, staff of the International Livestock Research Institute (ILRI) and many other CGIAR centres and research programs are attending the 6th Africa Agriculture Science Week (AASW6), which is being hosted by the Forum for Agricultural Research in Africa (FARA) and the Government of Ghana and runs from Monday–Saturday, 15–20 Jul 2013.
CGIAR is a global partnership for a food-secure future that conducts and disseminates research to improve the lives, livelihoods and lands of the world’s poorest people. CGIAR research is conducted by 15 of the world’s leading agricultural development research centres and 16 global research programs, all of them partnering with many stakeholders in Africa. More than half of CGIAR funding (52% in 2012) targets African-focused research.

The theme of next week’s AASW6 is ‘Africa Feeding Africa through Agricultural Science and Innovation’. CGIAR is supporting African-driven solutions to food security by partnering with FARA and the African Union, the Comprehensive Africa Agriculture Development Programme (CAADP), sub-regional organizations, national agricultural research systems and many other private and non-governmental as well as public organizations.

ILRI and livestock issues at AASW6

Ten ILRI scientists and staff will briefly speak and then engage with other participants in a side event ILRI is organizing at AASW6 on the topic of Livestock research for Africa’s food security. This three-hour morning side event will be facilitated by ILRI’s knowledge management and communication specialist, Ewen Le Borgne, and will be highly participatory in nature.

If you plan to attend this session, please shoot an email confirmation to Teresa Werrhe-Abira(t.werrhe-abira [at] cgiar.org) so we can organize refreshments.

And if you’d like to use this opportunity to talk with or interview one of the ILRI staff members below, or just meet them, please do so! ILRI communication officers Muthoni Njiru (m.njiru [at] cgiar.org) and Paul Karaimu (p.karaimu [at] cgiar.org) will be on hand at the ILRI side session (and you’ll find one or both at the CGIAR booth most of the rest of the week) to give you any assistance you may need.

Among the speakers at the ILRI side session will be the following.

Jimmy Smith: Livestock and the global development agenda

Jimmy Smith, a Canadian, became director general of ILRI in Oct 2011. Before that, he worked for the World Bank in Washington, DC, leading the Bank’s Global Livestock Portfolio. Before joining the World Bank, Smith held senior positions at the Canadian International Development Agency. Still earlier in his career, he worked at ILRI and its predecessor, the International Livestock Centre for Africa (ILCA), where he served as the institute’s regional representative for West Africa and subsequently managed the ILRI-led Systemwide Livestock Programme of the CGIAR, involving ten CGIAR centres working at the crop-livestock interface. Before his decade of work at ILCA/ILRI, Smith held senior positions in the Caribbean Agricultural Research and Development Institute (CARDI). Smith is a graduate of the University of Illinois at Urban-Champaign, USA, where he completed a PhD in animal sciences. He was born in Guyana, where he was raised on a small mixed crop-and-livestock farm.

John McIntire: Africa’s integrated crop-livestock systems

John McIntire (USA) is ILRI deputy director general for research-integrated sciences. He obtained a PhD in agricultural economics in 1980 from Tufts University using results of farm-level field studies of smallholder crop production in francophone Africa. He subsequently served as an economist for the International Food Policy Research Institute (IFPRI), in Washington, DC, and the West Africa Program of the International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), in Burkina Faso and Niger, and the International Livestock Centre for Africa (ILCA), one of ILRI’s two predecessors, in Ethiopia. He is co-author of Crop Livestock Integration in Sub-Saharan Africa (1992), a book still widely cited 20 years later. McIntire joined the World Bank in 1989, where he worked (in Mexico, Côte d’Ivoire, Senegal, The Gambia, Cape Verde, Guinea, Tanzania, Uganda and Burundi) until his retirement in 2011. In 2011, he became the second person to receive both the Bank’s ‘Good Manager Award’ and ‘Green Award for Environmental Leadership’.

Shirley Tarawali: ILRI’s new long-term strategy, 2013–2022

Shirley Tarawali (UK) is ILRI director of institutional planning and partnerships. Before taking on this role, Tarawali was director of ILRI’s People, Livestock and the Environment Theme, with responsibilities spanning sub-Saharan Africa and Asia. She holds a PhD in plant science from the University of London. Previously, Tarawali held a joint appointment with ILRI and the International Institute of Tropical Agriculture (IITA), based in Ibadan, Nigeria. Her fields of specialization include mixed crop-livestock and pastoral systems in sub-Saharan Africa and Asia.

Delia Grace: Food safety and aflatoxins

Delia Grace (Ireland) is an ILRI veterinarian and epidemiologist who leads a program at ILRI on food safety and zoonosis. She also leads a flagship project on ‘Agriculture-Associated Diseases’, which is a component of the CGIAR Research Program on Agriculture for Nutrition and Health, led by the International Food Policy Research Institute (IFPRI), USA. Grace has broad developing-country expertise in food safety, risk factor analysis, ecohealth/one health, gender and livestock, participatory methods, randomized trials and health metrics.

Questions Grace will address in ILRI’s side event are:
What are risk-based approaches to food safety in informal markets where most of the poor buy & sell?
How should we deal with food safety dynamics: livestock revolution, urbanization, globalization?
How can we better understand the public health impacts of aflatoxins?

Polly Ericksen: Vulnerability and risk in drylands

Polly Ericksen (USA) leads drylands research at ILRI and for the CGIAR Research Program on Drylands Systems in East and Southern Africa, where, in the coming years, the program aims to assist 20 million people and mitigate land degradation over some 600,000 square kilometres. That CGIAR research program as a whole is led by the International Centre for Agricultural Research in the Dry Areas (ICARDA), Syria. Ericksen also leads a Technical Consortium for Ending Drought Emergencies and Building Resilience to Drought in the Horn of Africa. Her broad expertise includes food systems, ecosystem services and adaptations to climate change by poor agricultural and pastoral societies.

Questions Ericksen will address in ILRI’s side event are:
How can commercial pastoral livestock production lead to growth in risk-prone drylands?
Is there a long-term role for livestock insurance in pastoral production systems?

Iain Wright, Alan Duncan and Michael Blümmel: The biomass crisis in intensifying smallholder systems

Iain Wright (UK) is ILRI director general’s representative in Ethiopia and head of ILRI’s Addis Ababa campus, where over 300 staff are located. He also directs ILRI’s Animal Science for Sustainable Productivity program, a USD15-million global program working to increase the productivity of livestock systems in developing countries through high-quality animal science (breeding, nutrition and animal health) and livestock systems research. Before this, Wright served as director of ILRI’s People, Livestock and the Environment theme. And before that, from 2006 to 2011, he was ILRI’s regional representative for Asia, based in New Delhi and coordinating ILRI’s activities in South, Southeast Asia and East Asia. Wright has a PhD in animal nutrition. Before joining ILRI, he managed several research programs at the Macaulay Institute, in Scotland.

Alan Duncan (UK) is an ILRI livestock feed specialist and joint leader of the Nile Basin Development Challenge Programme. Duncan joined ILRI in 2007, also coming from Scotland’s Macaulay Institute. Duncan has a technical background in livestock nutrition but in recent years has been researching institutional barriers to feed improvement among smallholders. He also works on livestock-water interactions, which are a key issue in Ethiopia, where he is based, particularly in relation to the competition for water occurring between the growing of livestock feed and that of staple crops. Duncan manages a range of research-for-development projects and acts as ILRI’s focal point for the CGIAR Research Program on Integrated Systems for the Humid Tropics, which is led by the International Institute of Tropical Agriculture (IITA), Nigeria.

Michael Blümmel (Germany) is an ILRI animal nutritionist with PhD (1994) and Habilitation (2004) degrees from the University of Hohenheim, in Germany. He has more than 20 years of experience in research, teaching and development in Europe, the US, Africa and Asia. Blümmel’s major research interests include feeding and feed resourcing at the interface of positive and negative effects from livestock, multi-dimensional crop improvement concomitantly to improve food, feed and fodder traits in new crop cultivars, and optimization of locally available feed resources through small business enterprises around decentralized feed processing.

A question they will address in ILRI’s side event is:
What are the options for sustainable intensification through livestock feeding?

Ethel Makila: Mobilizing biosciences for a food-secure Africa

Ethel Makila (Kenya) is ILRI communications officer for the Biosciences eastern and Central Africa-ILRI Hub. She is a graphic designer expert in development communication, media and education. At the BecA-ILRI Hub, she is responsible for increasing awareness of the Hub’s activities, facilities and impacts among African farmers, research institutes, government departments, Pan-African organizations and the international donor and research communities.

Questions Makila will address in ILRI’s side event are:
How can we build bio-sciences capacity in Africa to move from research results to development impacts?
How can we keep the BecA-ILRI Hub relevant to the research needs and context of African scientists?

Suzanne Bertrand: Vaccine biosciences

Suzanne Bertrand (Canada) is ILRI deputy director general for research-biosciences. With a PhD in plant molecular biology from Laval University, Bertrand began her career as a scientist with Agri-Food Canada, working on forage plants. Her focus shifted rapidly from laboratory-based research to application of modern agri-technology in the developing world. Her overseas assignments included spells in the People’s Republic of China and Tunisia. She spent six years in the USA, first as research assistant professor at North Carolina State University, and then as a founding principal for a biotechnology start-up company. She then joined Livestock Improvement (LIC), a large dairy breeding enterprise in New Zealand, where she managed LIC’s Research and Development Group, delivering science-based solutions in the areas of genomics, reproductive health, animal evaluation and commercialization to the dairy sector. In 2008, Bertrand became director, International Linkages for the Ministry of Research, Science and Technology in New Zealand. She was later chief executive officer for NZBIO, an NGO representing the interests and supporting growth of the bioscience sector in New Zealand.

Questions Bertrand will address in ILRI’s side event are:
How do we stimulate and sustain an African vaccine R&D pathway to achieve impact?
How can we grow a biotech and vaccine manufacturing sector in Africa?

Find more information about AASW6, including a full agenda, and follow the hashtag #AASW6 on social media.

Full list of ILRI participants at AASW6

Jimmy Smith, director general, based at ILRI’s headquarters, in Nairobi, Kenya
John McIntire, deputy director general-Integrated Sciences, Nairobi
Suzanne Bertrand, deputy director general—Biosciences, Nairobi
Shirley Tarawali, director of Institutional Planning and Partnerships, Nairobi
Iain Wright, director of ILRI Animal Sciences for Sustainable Agriculture Program, based at ILRI’s second principal campus, in Addis Ababa, Ethiopia
Abdou Fall, ILRI regional representative and manager of conservation of West African livestock genetic resources project, based in Senegal
Iheanacho (Acho) Okike, manages project of the CGIAR Research Program on Livestock and Fish, based in Ibadan, Nigeria
Appolinaire Djikeng, director of the Biosciences eastern and Central Africa-ILRI Hub, Nairobi
Iddo Dror, head of ILRI Capacity Development, Nairobi
Delia Grace, leads ILRI Food Safety and Zoonosis program and also an ‘Agriculture-Associate Diseases’ component of CRP on Agriculture for Nutrition and Health, Nairobi
Joy Appiah, former student in ILRI Safe Food, Fair Food project; ILRI is supporting his participation at AASW6; he is now at the University of Ghana
Polly Ericksen, leads dryands research within ILRI Livestock Systems and Environment program, serves as ILRI focal point for two CGIAR research programs—on Climate Change, Agriculture and Food Security and Dryland Systems—and leads a Technical Consortium for Building Resilience to Drought in the Horn of Africa, based in Nairobi
Katie Downie, coordinator of the Technical Consortium for Building Resilience to Drought in the Horn of AfricaHorn of Africa, Nairobi
Alan Duncan, leads feed innovations research within ILRI Animal Sciences for Sustainable Agriculture program and serves as ILRI focal point for the CGIAR Research Program on the HumidTropics, Addis Ababa
Michael Blümmel, leads feed resources research within ILRI Animal Sciences for Sustainable Agriculture program, based at ICRISAT, in Hyderabad, India
Allan Liavoga, deputy program manager of Bio-Innovate, Nairobi
Dolapo Enahoro, agricultural economist within ILRI Policy, Trade and Value Chains program, based in Accra

Communications support

Ewen LeBorgne, ILRI knowledge management and communications specialist; is facilitating ILRI’s side session at AASW6 on 15 Jul; based in Addis Ababa
Muthoni Njiru, ILRI communications officer in ILRI Public Awareness unit: overseeing media relations, exhibit materials, video reporting at AASW6; Nairobi
Paul Karaimu, ILRI communications writer/editor in ILRI Public Awareness unit: overseeing blogging, photography, video reporting at AASW6; Nairobi
Ethel Makila, ILRI communications specialist for the BecA-ILRI Hub, Nairobi
Albert Mwangi, ILRI communications specialist for Bio-Innovate, Nairobi

plus

Cheikh Ly, ILRI board member, from Senegal, veterinary expert at FAO, based in Accra, Ghana
Lindiwe Majele Sibanda, ILRI board chair, from Zimbabwe, livestock scientist, agricultural policy thinker, and CEO and head of mission of the Food, Agriculture and Natural Resources Policy Analysis Network (FANRPAN), based in Pretoria, South Africa

Experts meet to share tactics in fight against ‘goat plague’: Filmed highlights

Posted on May 20, 2013 by Paul Karaimu

Watch this short (3:50 minutes) film on the views of participants at a recent meeting to coordinate research strategies for a disease of small ruminants known as peste des petits ruminants, or PPR. This second meeting of the Global Peste de Petits Ruminants (PPR) Research Alliance, held 29–30 April 2013 in Nairobi, Kenya, brought together over 60 livestock experts from across the world.

The harm caused by PPR, also known as ‘goat plague’ because it is closely related to ‘cattle plague’, or rinderpest, has been increasing in recent years, especially across Africa and Asia. This infectious viral disease of sheep and goats poses a major threat to the livelihoods of smallholder farmers. The disease is highly contagious, with roughly an 80 per cent mortality rate in acute cases.

‘We’re bringing together the relevant animal health experts so that we can find ways to better coordinate the diverse research on PPR, and determine the fastest and most effective and efficient ways to better control it in different developing-country regions and circumstances’, said Geoff Tooth, the Australian High Commissioner to Kenya.

The meeting was co-hosted by four institutions: the African Union-Interafrican Bureau for Animal Resources (AU-IBAR), the Australian Agency for International Development (AusAID), the Biosciences eastern and central Africa-ILRI Hub (BecA-ILRI Hub) and the International Livestock Research Institute (ILRI).

A current AusAID-funded project being conducted by the BecA-ILRI Hub and Australia’s Commonwealth Scientific, Industrial and Research Organisation (CSIRO) has supported development of a thermostable vaccine that is now being piloted in vaccination campaigns in Sudan and Uganda, with similar work proposed for Ethiopia.

Read more about efforts to develop a pan-African strategy to fight goat plague: https://www.ilri.org/node/1344

New vaccine launched today to protect Kenyan cattle against East Coast fever

Posted on December 7, 2012 by Susan MacMillan

Mrs Kivuti and her dairy cow in Kenya (on Flickr by Jeff Haskins).

Today is a red-letter day for livestock keepers in Kenya. A vaccine is being launched by the Kenya Department of Veterinary Services that will help Kenyan farmers protect their dairy and other cattle against East Cost fever. The launch is being held in Kenya’s Kitale town.

For four decades, the Nairobi-based International Livestock Research Institute (ILRI) and its predecessor (the International Laboratory for Research on Animal Diseases, ILRAD) have conducted research on the lethal tick-borne cattle disease known as East Coast fever. ILRI’s work has focused on developing a new-generation ‘subunit’ vaccine, comprising molecular components of the causative parasite, while also developing molecular tools to enhance the quality of an infection-and-treatment (ITM) immunization method, consisting of whole live parasites.

The ITM vaccine was developed first by the former East African Veterinary Research Organisation, at Muguga, Kenya, between 1967 and 1977, now known as the Veterinary Research Centre, which is part of the Kenya Agricultural Research Institute (KARI) and which has continued to refine the vaccine.

ILRI produced the first commercial batch of the ITM vaccine in the late 1990s, at the request of the Food and Agriculture Organization of the United Nations. A decade later, on request from regional stakeholders, ILRI produced a second batch, which is now being used in East Africa. ILRI and KARI also supported Kenya’s Director of Veterinary Services (DVS) in his department’s successful trials that have confirmed the safety and effectiveness of the ITM vaccine, thus making way for the launch of its national distribution today.

Two ILRI scientists, Phil Toye and Henry Kiara, that have been involved in this research for many years are attending the launch. They say that East Coast fever continues to cause major economic and social losses to families in eastern, central and southern Africa.

Of the 46 million cattle in this region almost half are at risk from this disease, say Toye and Kiara.

‘ILRI’s work has focused on better understanding of the biology of the parasite that causes the disease and the host immune responses to infection. While the ITM vaccine was developed in the early 1970s at Muguga, Kenya, the vaccine was not readily taken up due to inadequate understanding of the biology and epidemiology of the diseases at the time.’

Scientists in KARI and ILRI continued to refine the technology to the point where it was deemed safe and effective to distribute the vaccine on a commercial basis to farmers. ILRI will continue working with Directors of Veterinary Services in the region to address any research questions that may arise as we continue to use this technology.

It gives me great pleasure today to congratulate the Kenya Department of Veterinary Services on this great occasion of the launch of the East Coast fever vaccine. ILRI is proud to have played a role in this and will continue to offer any research support needed to keep Kenya’s cattle safe from this deadly disease.—Phil Toye

Rinderpest: Scourge of pastoralists defeated, at long last, by pastoralists

Posted on September 18, 2012 by Susan MacMillan

A timeline of major events in the history of rinderpest in Africa from its introduction in 1887, in military cattle brought to Eritrea to feed troops, to the declaration of rinderpest’s eradication in 2011. RP, rinderpest. (Illustration credit: Figure 1 in ‘Rinderpest eradication: Appropriate technology and social innovations’, 2010, by Jeffrey Mariner et al. Science 337, 1309.)

The invention of sex and death, evolutionary biologists tell us, allowed organisms to escape wholesale extermination by parasitic infections. The invention of antibiotics and other miracles of modern medicine allows many of us, particularly in rich countries, to think we can escape most disease, if not death. This of course is over-optimistic and flies in the face of all of human history. Disease has altered those histories, stamped whole continents with its imprint, shaped global affairs—bubonic plague in 14th-century Europe, smallpox in the Americas in the 16th century following European invasion, potato blight in 19th-century Ireland, the Spanish flu pandemic that circled the world in 1918, malaria and HIV/AIDS in Africa today.

Some of the most important diseases have killed human populations indirectly, by annihilating the crops and animals that sustained us. This happened when late blight affected the potato crop in Ireland in the 1840s, killing some 1 million people and causing another 1.5 million to emigrate in The Great Hunger, and when brown spot of rice ruined crops in Bangladesh and eastern India in 1943, leading to the deaths of 2 million or more people in The Bengal Famine.

Among the latter ‘food plagues’ is a remarkably little-known viral disease of cattle and other ungulates that ‘has been blamed for speeding the fall of the Roman Empire, aiding the conquests of Genghis Khan and hindering those of Charlemagne, opening the way for the French and Russian revolutions, and subjugating East Africa to colonization (Rinderpest, scourge of cattle, is vanquished, New York Times, 27 Jun 2011).

Rinderpest, a German term meaning ‘cattle plague’, is a viral disease related to measles (recent evidence suggests the measles virus may have diverged from the rinderpest virus during the Middle Ages). It is arguably the most important animal disease historically. It entered the Horn of Africa from the port of Massawa, in what is now Eritrea, in 1887 with an invading Italian army that was importing Indian cattle for food and draft power.

The virus exploded so fast that it reached South Africa within a decade (and is considered one of the factors that impoverished Boer farmers as war with the English approached). It doomed East Africa’s wandering herders, subsisting on milk mixed with cow blood. Historians believe a third of them or more starved to death—Rinderpest, scourge of cattle, is vanquished, New York Times, 27 Jun 2011.

Killing animals within days of infection, the rinderpest epidemic emptied East Africa of most of its large grazing animal populations, wiping out 80–90 per cent of the region’s cattle, which, it is argued, left the remaining population too weak from hunger to oppose European colonialism.

Rinderpest struck East Africa in 1890, and in two years 95 percent of the buffalo and wildebeest there had died. So began a series of events of such profound ecological importance that the repercussions are still being felt today.—A R E Sinclair and M Norton-Griffiths, editors, Serengeti: Dynamics of an Ecosystem, 1979.

Journalist Fred Pearce gives more details.

Great pastoral civilizations across the continent were shattered. Central African cattle-rearing tribes like the Tutsi and Karamajong starved, along with Sudanese nations like the Dinka and Bari, West Africans like the Fulani, and southern Africans like the Nama and Herero. The folklore of the Maasai of East Africa tells of the enkidaaroto, the “destruction,” of 1891. They lost most of their cattle, and two-thirds of the Maasai died. One elder later recalled that the corpses were “so many and so close together that the vultures had forgotten how to fly.”

Many of these societies never recovered their numbers, let alone their wealth and power. Rinderpest served up the continent on a plate for European colonialists. In its wake, the Germans and British secured control of Tanzania and Kenya with barely a fight. In southern Africa, the hungry and destitute Zulus migrated to the gold mines of Witwatersrand, helping to create the brutal social divide between black and white from which apartheid sprang.

It is an extraordinary story, rarely told. . . .

Fred Pearce: Why Africa’s national parks are failing to save wildlife, Yale Environment 360, 19 Jan 2010.

Dan Charles, of National Public Radio, in the USA, reports on an article published in Science this month demonstrating that it was African cattle herders that wiped this ancient plague from the face of the Earth.

‘Twice in all of history, humans have managed to eradicate a devastating disease. You’ve heard of the first one, I suspect: smallpox. But rinderpest? . . .

‘In this week’s issue of the journal Science, several of the architects of rinderpest’s elimination lay out the reasons for their success. The key innovation wasn’t technological, they say. It was social and cultural.

‘Technology certainly played a part. Half a century ago, a British veterinarian named Walter Plowright, working in Kenya, created the first truly effective and safe vaccine for rinderpest. . . .

‘Later, Jeffrey Mariner of the Tufts Cummings School of Veterinary Medicine, developed a version of the vaccine that didn’t need to be refrigerated, allowing veterinarians to use it far from roads and electricity.

‘Yet the disease persisted in Africa, surviving in remote areas plagued by weak government and chronic conflict, such as southern Sudan and parts of Uganda, Ethiopia, and Somalia. Veterinarians rarely ventured into those areas, and it was hard to know where vaccinations were even needed because government officials were reluctant to report outbreaks.

Mariner, who now works at the International Livestock Research Institute in Kenya, says that ultimately, the skills and knowledge of nomadic cattle herders who lived in those hard-to-reach areas were the keys to cracking the rinderpest puzzle.

“Those farmers could tell us where outbreaks were occurring,” Mariner tells The Salt, speaking by phone from Nairobi. In addition, some nomadic farmers got training as “community animal health workers” and were able to carry out vaccinations themselves. They proved better at the job than veterinarians, in part because they knew their animals. . . .

Tom Olaka, a community animal health worker in Karamajong, northern Uganda, was part of a vaccination campaign in remote areas of the Horn of Africa that drove the cattle plague rinderpest to extinction in 2010 (photo credit Christine Jost).

‘Tom Olaka, a community animal health worker in the border region between Uganda, Sudan, and Kenya, identified and reported the last outbreak of rinderpest in 2000. The virus was officially declared extinct last year. Around the world, cattle farmers can breathe just a little easier.’

Read the whole article by Dan Charles at NPR: How African Cattle Herders Wiped Out An Ancient Plague, 14 Sep 2012.

Read the ILRI News Blog about this: New analysis in ‘Science’ tells how world eradicated deadliest cattle plague from the face of the Earth, 13 Sep 2012.

Read the paper in Science (subscription required to read full text): Rinderpest eradication: Appropriate technology and social innovations, by Jeffrey Mariner, James House, Charles Mebus, Albert Sollod, Dickens Chibeu, Bryony Jones, Peter Roeder, Berhanu Admassu, Gijs van ’t Klooster, 14 September 2012, Vol. 337 no. 6100 pp. 1309–1312, DOI: 10.1126/science.1223805.

Read previous articles on the ILRI News and Clippings blogs about the eradication of rinderpest:

ILRI’s Jeff Mariner speaks on what he learned from the eradication of rinderpest–and his new fight against ‘goat plague’, 15 Sep 2012.

Goat plague next target of veterinary authorities now that cattle plague has been eradicated, 4 Jul 2011.

Deadly rinderpest virus today declared eradicated from the earth–’greatest achievement in veterinary medicine’, 28 Jun 2011.

After successful eradication of rinderpest, African researchers now focus on peste des petits ruminants, the most urgent threat to African livestock, 22 Nov 2010.

Why technical breakthroughs matter: They helped drive a cattle plague to extinction, 28 Oct 2010.

New analysis in ‘Science’ tells how world eradicated deadliest cattle plague from the face of the Earth

Posted on September 13, 2012 by Susan MacMillan

In a new analysis in Science, ILRI researcher Jeffrey Mariner describes how the world eradicated deadliest cattle plague, the second such success after smallpox. The authors of the paper reveal the essential role of Africa’s nomadic herders in ridding the world of rinderpest. Above, an Afar community animal health worker in 1993 describes the appearance and characteristics of rinderpest in cattle (photo by Jeff Mariner).

A new analysis published today in Science traces the recent global eradication of the deadliest of cattle diseases, crediting not only the development of a new, heat-resistant vaccine, but also the insight of local African herders, who guided scientists in deciding which animals to immunize and when. The study provides new insights into how the successful battle against rinderpest in Africa, the last stronghold of the disease, might be applied to similar diseases that today ravage the livestock populations on which the livelihoods of one billion of the world’s poor depend.

Capable of wiping out a family’s cattle in just a few days, rinderpest was declared vanquished in May 2011. After smallpox, it is only the second disease (and first livestock disease) ever to be eradicated from the earth.

‘The elimination of rinderpest is an enormous triumph against a disease that has plagued animals and humankind for centuries’, said Jimmy Smith, director general of the International Livestock Research Institute (ILRI). ‘Science succeeded despite limited resources, and we now know how. We are committed to applying the lessons in this study to making progress against other similarly destructive livestock diseases.’

According to the analysis, which was conducted by international scientists coordinated by ILRI, and published this week in Science, the eradication of rinderpest happened thanks to the development of an effective temperature-stable vaccine, collaborations between veterinary health officials and cattle farmers to deliver those vaccines, and reliance on the knowledge and expertise of the local herders to determine the location and movement of outbreaks.

The cattle plague and its path of destruction
Rinderpest, known as ‘cattle plague’ in English, is thought to have had its origin in the dense cattle herds of Central Eurasia more than two millennia ago and subsequently spread through warfare and trade to cattle in Europe, Asia and eventually Africa. Caused by a virus related to the one that causes measles and canine distemper, rinderpest could infect cows, water buffalos and other cloven-hoofed animals, leading to a high fever, severe diarrhea, then dehydration and emaciation. The pathogen could kill 90 per cent of a herd, wiping out an entire farm’s livestock in just a matter of days. There was no treatment.

While rinderpest is not dangerous to human health, its impact on humanity has been significant. Its path of destruction has been linked to many history-changing events such as the fall of the Roman Empire, the French Revolution and famines throughout Africa since the 19th century. Indeed, nearly three-quarters of the rural poor and some one-third of the urban poor depend on livestock for their food, income, traction, manure or other services. Livestock provide poor households with up to half their income and between 6 and 35 per cent of their protein consumption. The loss of a single milking animal can affect a family’s economic health, while depriving it of a primary source of nutrition.

Road to eradication
The first major contributing factor to eradication, as identified by the analysis, was a major improvement made to an existing rinderpest vaccine. While the original vaccine was safe, effective, affordable, and easy to produce, it needed to be refrigerated—making it nearly impossible to transport it to remote rural villages. With the development of a new heat-resistant vaccine formulation in 1990 that could be stored at 37 °C for eight months, and in the field without refrigeration for 30 days, scientists had a tool that would become the cornerstone of the eradication effort in remote pastoral areas of Africa.

But according to ILRI’s Jeffrey Mariner, the analysis’ lead author and inventor of the temperature-stable rinderpest vaccine, it was the role played by pastoralists that really turned rinderpest on its head.

As part of a public-private-community partnership, Mariner and colleagues trained what they called community-based animal health workers, or CAHWs—local pastoralists who were willing to travel on foot and able to work in remote areas—on how to deliver the new vaccine. These CAHWs carried the vaccine from herd to herd, immunizing all the cattle in their communities.

The local herders performed as well, if not better, than did veterinarians at vaccinating the herds—in fact often achieving higher than 80 per cent herd immunity in a short time—remarkable for a disease that had plagued most of the world for millennia. Indeed, it turned out that the pastoralists were not only very, very good at delivering the vaccine, but that they also knew more about the disease and how to stop it than many of the experts.

‘We soon discovered that the livestock owners knew more than anyone—including government officials, researchers or veterinarians—where outbreaks were occurring’, Mariner said. ‘It was their expertise about the sizes of cattle herds, their location, seasonal movement patterns and optimal time for vaccination that made it possible for us to eradicate rinderpest.’

Based on their immense expertise about migratory patterns and in recognizing early signs of infection, the herders were able to pinpoint, well before scientists ever could, where some of the final outbreaks were occurring—often where conventional surveillance activities had failed to disclose disease. Harnessing this knowledge of rinderpest through ‘participatory surveillance’ of outbreaks to CAHW delivery of vaccination proved to be the most successful approach to monitoring and controlling the disease. It effectively removed the disease from some of the hardest-to-reach, but also most disease-ridden, communities.

Applying rinderpest lessons to other diseases
While livestock and those who depend on them for food, transportation and economic stability are now safe from one major pathogen, they continue to be plagued by a number of other dangerous and debilitating diseases—some as deadly as rinderpest.

The international animal health community is now gearing up to address the next major constraint to livestock livelihoods in Africa and Asia. In their analysis, Mariner and colleagues consider how the lessons learned from battling rinderpest can be applied to protect livestock from other infectious agents—particularly peste des petits ruminants (PPR), also known as ‘goat plague’. Strategies to address PPR using the lessons from rinderpest have been developed and action is under way to mobilize international support for a coordinated program to tackle PPR. As a next step, ILRI and the Africa Union/Interafrican Bureau for Animal Resources are planning to host the next meeting of the PPR Alliance, a partnership of research and development organizations who prioritize PPR, in Nairobi in early 2013.

A dangerous virus that can destroy whole flocks of sheep and goats, PPR threatens livestock owners in Africa, Asia and the Middle East, in particular. As with rinderpest, a sheep or goat infected with PPR will come down with a high fever and will stop eating, leading to severe diarrhea and death. Eventually, it will take down the entire herd of the animals, which are equal to cattle in their importance to the poor. And controlling PPR is made challenging by the short life span and heavy trading of sheep and goats—making it difficult to keep the disease in check and preventing its spread to new areas.

Nonetheless, the lessons of rinderpest eradication have begun to have an impact on the toll exacted by goat plague. Participatory surveillance methods are now applied in many countries, CAHWs are now frequently involved in vaccination campaigns and ILRI has developed a temperature-stable vaccine that can be transported to rural farms and has started to put into place training programs for shepherds and farmers in Uganda and Sudan to deliver it.

Eventually, these same lessons could be applied to other livestock diseases such as foot-and-mouth disease—even some that have recently jumped to humans, like avian flu. Such ‘zoonotic’ diseases are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year, primarily in low- and middle-income countries.

Read previous articles on this blog about the eradication of rinderpest: Goat plague next target of veterinary authorities now that cattle plague has been eradicated, 4 Jul 2011.

Deadly rinderpest virus today declared eradicated from the earth–’greatest achievement in veterinary medicine’, 28 Jun 2011.

After successful eradication of rinderpest, African researchers now focus on peste des petits ruminants, the most urgent threat to African livestock, 22 Nov 2010.

Why technical breakthroughs matter: They helped drive a cattle plague to extinction, 28 Oct 2010.

American agricultural economist Tom Randolph to lead new CGIAR Research Program on Livestock and Fish

Posted on October 24, 2011 by Susan MacMillan

Tom Randolph, an agricultural economist at ILRI, speaks with former ILRI project manager Oumar Diall while attending a 2006 workshop in Bamako, Mali, on controlling trypanosomosis drug resistance, a project he and Diall led for several years in West Africa (photo credit: ILRI/Stevie Mann).

Tom Randolph has been named director of a newly established CGIAR Research Program on Livestock and Fish. Jimmy Smith, new director general of the International Livestock Research Institute (ILRI), a position he took up on 1 October 2011, announced Randolph’s appointment on 13 October 2011.

ILRI leads this CGIAR research program, which is one of several new multi-institutional research programs initiated by the Consultative Group on International Agricultural Research (CGIAR). In this program, which aims to provide more meat, milk and fish by and for the poor, ILRI will be collaborating with other scientists and staff from three of its sister CGIAR centres—the International Center for Tropical Agriculture (CIAT), based in Cali, Colombia; the International Center for Agricultural Research in the Dry Areas (ICARDA), based in Aleppo, Syria; and the WorldFish Center, based in Penang, Malaysia. Many other strategic partners will play key roles in implementing the program in several ‘livestock value chains’ and countries targeted by the new project.

Randolph helped lead the collaborative processes employed over the last two years to develop the concept and subsequent full proposal for this research program.

Before this appointment, Randolph headed a team conducting research on smallholder competitiveness in changing markets under ILRI’s Market Opportunities Theme. His research interests and contributions at ILRI have been varied, including studies at the interface of animal and human health and assessments of the impacts of agricultural problems and the research conducted to address them, including evaluations of the impacts of tick and tick-borne diseases, animal health delivery systems, ILRI’s East Coast fever vaccine development research, the contributions economics and epidemiology can make to animal disease control and the control of bird flu in sub-Saharan Africa.

One of the projects Randolph led has helped to reduce parasite resistance to drugs used to control trypanosomosis (animal sleeping sickness) in the cotton belt of West Africa. This project established a clear picture of the distribution of potential resistance across a zone from eastern Guinea to western Burkina Faso, highlighting the importance of tsetse ecology, farming systems, accessibility to veterinary services and pharmaceutical products, and cattle breed in influencing drug use and misuse. Under Randolph’s leadership, this project evolved from a primary focus on the biological issue to a holistic understanding of the complex epidemiological and socioeconomic factors at farm, local, national and regional levels that influence the problem and determine the ability to address it.

Among his more recent projects is a groundbreaking assessment of the relations between dairy intensification, gender and child nutrition among smallholder farmers in the Rift Valley Province of Kenya; this project is investigating the pathways between dairy intensification and child nutrition.

An American from upstate New York, Randolph received an undergraduate degree in Chinese studies in 1976, after which he spent six years teaching English in Zaire with the Peace Corps. On his return to the United States, Randolph pursued an MSc and PhD in agricultural economics from Cornell University. His doctoral dissertation was based on field work he conducted in Malawi with the Harvard Institute for International Development, looking at the impact of agricultural commercialization on child nutrition in smallholder households. His thesis earned the American Agricultural Economics Association’s Outstanding PhD Dissertation Award. He subsequently joined the West African Rice Development Association (WARDA, now Africa Rice Centre), in Senegal, as a Rockefeller-funded post-doctoral fellow, later becoming policy economist and policy support program leader at WARDA’s Côte d’Ivoire headquarters.

Randolph joined ILRI in 1998 and will remain based at ILRI’s Nairobi, Kenya, headquarters as he directs this new multi-country and multi-institutional CGIAR Research Program on Livestock and Fish.

World Bank president says it’s time to push the CGIAR agricultural research agenda

Posted on July 7, 2011 by Susan MacMillan

Robert Zoellick, president of the World Bank (image on Flickr by International Monetary Fund).

Robert Zoellick, president of the World Bank, spoke today (6 July 2011) at the 40-year-anniversary celebrations of the Consultative Group on International Agricultural Research (CGIAR) at the World Bank in Washington, DC. His presentation followed a film about the historical beginnings of the CGIAR, including interviews of Norman Borlaug and Robert McNamara.

‘Both Norman Borlaug and Robert McNamara believed that it is possible to defeat hunger,’ Zoellick said. ‘They both worked to boost food production through science. And they both died within a few months of each other in 2009.’

Zoellick said that agriculture is a subject of strong personal interest for him; he grew up around farm families in the American midwest. And he said few things were as satisfying for him as speaking to farm families that had doubled, tripled or quadrupled their incomes through improved farm practices, which in turn rely on agricultural science.

Zoellick said that high food prices today are pushing 44 million people into poverty, and the global population is expected to reach 9 billion by 2050.

‘We’ll have to increase food production by 70% to feed everyone by mid-century,’ he said. ‘And we’ll have to do that with the rate of production increases dropping and in the face of climate change, which is predicted to decrease crop yields in Africa by 28%.’

Zoellick reported on some of the great achievements of the CGIAR over the last four decades. Among them, he cited the following work by the International Livestock Research Institute (ILRI) and its partners, including the Kenya Agricultural Research Institute.

There is now a vaccine for East Coast fever, which kills 1 cow every 30 seconds in 11 countries of Africa. The vaccine is expected to save more than a million cattle, with benefits worth up to USD270 million a year in the countries where the disease is now endemic.

‘I’ve been urging the G20 to put food first this year,’ said Zoellick. ‘One of my key messages at both G8 and G20 is the need to support agriculture and agricultural research.

“I see a 5-step challenge for the CGIAR,’ said Zoellick.
(1) Donor agencies increase funding to the CGIAR from USD670 million last year to USD1 billion by 2013.
(2) Donor agencies commit to multi-year predictable funding.
(3) Research institutions place greater focus on research to reduce post-harvest food losses (which can make up 20–50% of yields).
(4) Developing countries themselves increase their investments to agricultural research and development.
(5) Researchers and their supporters stand up for science and fight the current trend of cloaking ignorance in fashionable causes.

The moment is right to push the agricultural research agenda, Zoellick said. ‘The agricultural sector is fertile for innovation. And we can demonstrate the intimate links between this work and two of the big issues of our day—food security and climate change.’

Given the ammunition, he said, he’ll push this agenda forward.

Deadly rinderpest virus today declared eradicated from the earth–‘greatest achievement in veterinary medicine’

Posted on June 28, 2011 by Susan MacMillan

At the 79th General Session of the United Nations World Organisation for Animal Health (OIE), in Paris in May 2011, ILRI’s Jeff Mariner (second from right) stands among a group of distinguished people heading work responsible for the eradication of rinderpest, a status officially declared at this meeting (image credit: OIE).

Several world bodies are celebrating what is being described as ‘the greatest achievement in veterinary medicine’: the eradication of only the second disease from the face of the earth.

The disease is rinderpest, which means ‘cattle plague’ in German. It kills animals by a virus—and people by starving them through massive losses of their livestock.

‘In the nineteenth and twentieth centuries,’ reports the United Nations Food and Agriculture Organization (FAO), ‘the disease devastated parts of Africa, triggering extensive famines. . . . After decades of efforts to stamp out a disease that kept crossing national borders, countries and institutions agreed they needed to coordinate their efforts under a single, cohesive programme. In 1994, the Global Rinderpest Eradication Programme (GREP) was established at the UN Food and Agriculture Organization (FAO), in close association with the World Organization for Animal Health (OIE).

‘Excellent science, a massive vaccination effort, close international coordination and the commitment of people at all levels have helped make rinderpest eradication possible.

‘On June 28, 2011, FAO’s governing Conference will adopt a resolution officially declaring that rinderpest has been eradicated from animals worldwide. The successful fight against rinderpest underscores what can be achieved when communities, countries and institutions work together.’

Australian Peter Doherty, 1996 winner of the Nobel Prize for Medicine who served on the board of trustees of the International Laboratory for Research on Animal Diseases (ILRAD), a predecessor of ILRI (photo credit: published on the Advance website).

Australian Peter Doherty, an immunologist who is the only veterinarian to win the Nobel Prize, for Physiology or Medicine, in 1996, and who served as chair of the board of trustees research program of the International Laboratory for Research on Animal Diseases (ILRAD), a predecessor of the International Livestock Research Institute (ILRI), is attending the FAO ceremonies this week. In an interview with FAO, he said:

Vaccine research is currently a very dynamic area of investigation and with sufficient investment and the enthusiastic participation of industry partners at the “downstream” end, we can achieve even better vaccines against many veterinary and human diseases.

The Washington Post in May reported that ‘the World Organization for Animal Health, at its annual meeting in Paris on Wednesday, accepted documentation from the last 14 countries that they were now free of rinderpest. The organization, which goes by its French acronym, OIE, was started in 1924 in response to a rinderpest importation in Europe.

‘The most recent recorded outbreak occurred in Kenya in 2001. Much of the past decade has been spent looking for new cases, in domesticated animals and in the wild, wandering herds of ungulates, or hoofed animals, in East Africa. The last place of especially intense surveillance was Somalia, where the final outbreak of smallpox occurred in 1977.

‘“There are a huge number of unsung heroes in lots of countries that made this possible,” said Michael Baron, a rinderpest virologist at the Institute for Animal Health in Surrey, England. “In most places, they were ordinary veterinary workers who were doing the vaccination, the surveillance, the teaching.”

‘Three things made rinderpest eradicable. Animals that survived infection became immune for life. A vaccine developed in the 1960s by Walter Plowright, an English scientist who died last year at 86, provided equally good immunity. And even though the virus could infect wild animals, it did not have a reservoir of host animals capable of carrying it for prolonged periods without becoming ill.

‘In 1994, the FAO launched an eradication program that was largely financed by European countries, although the United States, which never had rinderpest, also contributed money. The effort consisted of massive vaccination campaigns, which were made more practicable when two American researchers made a version of the Plowright vaccine that required no refrigeration. . . .’

One of those researchers was Jeffrey Mariner, now working at ILRI, in Nairobi, Kenya. Mariner also helped in surveillance work ‘with a technique called “participatory epidemiology” in which outside surveyors meet with herdsmen and ask open-ended questions about the health of their animals and when they last noticed certain symptoms.

‘“It was local knowledge that really helped us trace back the last places where transmission occurred—sitting down underneath a tree in the shade, listening to storytelling,” said Lubroth, of the FAO. . . .’

Read the whole article in the Washington Post, Rinderpest, or ‘cattle plague,’ becomes only second disease to be eradicated, 27 May 2011.

Read FAO’s interview of Peter Doherty: Healthier animals, healthier people, June 2011.

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