ILRI’s capacity development priorities: Contribute your views

Posted on June 11, 2013 by ILRIComms

Graphic report of recent ILRI discussions on capacity development

The International Livestock Research Institute (ILRI) envisions a world where all people have access to enough food and livelihood options to fulfill their potential. ILRI’s strategy 2013–2022 defines capacity development at ILRI as both a strategic objective and a critical success factor, which involves the development of attitudes, skills, institutional set ups as well as knowledge in agricultural research and development.

As ILRI embarks on the implementation journey of its new strategy—including capacity development aspects—we seek feedback from our important stakeholders on their perception of our work in this area.

Please take 10 minutes to fill out this survey and provide us with your valuable inputs.

Thank you very much in advance!

If you have any queries, please contact Iddo Dror, head of capacity development at ILRI

Keepers of the flame: Women livestock keepers

Posted on June 3, 2013 by Susan MacMillan

Kenyan farmer Alica Waithira shares the responsibility for managing her farm with her family. Her brothers take on the lion’s share of growing food for the family and fodder for the livestock. Alica takes care of the livestock—six cows, five sheep and countless ‘free range’ chickens. Making sure her animals are healthy and productive is critical to her success (photo credit: Gates Foundation).

Women livestock keepers are key to global food security. Those working to support women in livestock development have just received some support of their own.

Small livestock are particularly important to women as they contribute to household food security and provide much-needed funds for school fees and other family-related expenses. — Kathleen Colverson, ILRI Program Leader for Livelihoods, Gender, Impact and Innovation

About 752 million of the world’s poor keep livestock to produce food, generate income, manage risks and build up assets. In rural livestock-based economies, women represent two-thirds (some 400 million people) of low-income livestock keepers. In the Gambia 52% of sheep owners and 67% of goat owners are women. In the mountains of Chiapas, Mexico, sheep husbandry is mainly women’s responsibility, providing 36% of household income through wool processing and sale. In Afghanistan, traditional backyard poultry activities are carried out entirely by women, who manage an average of 10 hens that produce some 60 eggs a year, sufficient for household consumption. And across the world’s regions and cultures, milking and milk processing are mainly undertaken by women.

Women perform up to 70% of agricultural work in many parts of the world but rarely receive either credit or access to the benefits of their work. — Kathleen Colverson, ILRI Program Leader for Livelihoods, Gender, Impact and Innovation

In spite of their heavy involvement in livestock farming, customary gender roles are often biased, hindering women’s access to resources and extension services and their participation in decision-making. One result is that women get less household income than their menfolk do from livestock farming.

To help redress this, staff of the United Nations Food and Agriculture Organization (FAO) have worked with the International Livestock Research Institute (ILRI) other organizations to support gender analysis in livestock projects and programs worldwide.

This group has just produced a booklet—Understanding and integrating gender issues into livestock projects and programmes—A checklist for practitioners—that identifies the main challenges faced by women in managing small stock, particularly poultry, sheep and goats, and in dairy farming. The booklet is an outcome of a consultative training workshop held in November 2011 in Addis Ababa, Ethiopia, involving four East African countries. The workshop participants shared and critically analysed country-specific experiences from a gender perspective. The booklet compiles this knowledge with the aim of helping livestock experts in the field to identify and address the main constraints faced by women and men both in managing small livestock and dairy farming.

The booklet includes a set of tips and gender analysis tools and a checklist that, through all the stages of a project cycle, offers gender-sensitive guidance.

Without women’s contributions to livestock systems, much of what is accomplished today in increasing food security would be lost. — Kathleen Colverson, ILRI Program Leader for Livelihoods, Gender, Impact and Innovation

Kathleen Colverson, ILRI Program Leader for Livelihoods, Gender, Impact and Innovation.

The Addis Ababa workshop was such a success that FAO is holding another regional training workshop this week (4–6 June 2013) in Bangkok attended by representatives from eight countries from Southeast Asia and Bangladesh; a second booklet, generated by the Bangkok workshop, is planned.

Significant inputs to the Addis Ababa workshop and subsequent booklet were made by gender experts from the International Livestock Research Institute (ILRI), including Jemimah Njuki, who facilitated the workshop. Njuki has since left ILRI and is now based in Dar-Es-Salaam, where she leads a 6-country ‘Women in Agriculture (Pathways)’ program for CARE. Other inputs were provided by staff of the International Fund for Agricultural Development (IFAD), the Global Alliance for Livestock Veterinary Medicines (GALVmed) and representatives of ministries of livestock, agriculture and fisheries in Kenya, Uganda and Tanzania.

Kathleen Colverson, who succeeded Jemimah Njuki as program leader at ILRI, is facilitating the livestock and gender workshop being held this week in Bangkok this week.

Read the booklet: Understanding and integrating gender issues into livestock projects and programmes: A checklist for practitioners, FAO, 2013.

View the playlist below of recent ILRI posters and slide presentations related to gender issues in livestock research for development. for more information about ILRI’s gender program, contact Kathleen Colverson at k.colverson [at] cgiar.org

Three presentations on livestock for–and in–development by ILRI director general Jimmy Smith

Posted on May 31, 2013 by Susan MacMillan

Wherefore ILRI? from ILRI

Here are three slide presentations recently made by Jimmy Smith, director general of the International Livestock Research Institute (ILRI).

(1) Wherefore ILRI?, presented at ILRI’s annual program meeting, in Addis Ababa, Ethiopia, 15 May 2013.

Key message

(2) The developing world’s smallholder livestock sector, presented at the Board of the International Federation for Animal Health, Brussels, 25 Apr 2013.

Key messages

Demand for livestock source foods is growing faster inthe in the developing than the developed world
Smallholder producers are now and will continue to be alarge part of the supply response for decades to come
Animal health constraints are binding in developing countries
As smallholder systems modernize, their need foranimal health and other inputs will grow
New opportunities exist for synergies between privateand public investments in animal health

(3) Livestock in developing countries: Animal health challenges and opportunities, presented at the General Assembly of the International Federation for Animal Health, Brussels, 25 Apr 2013.

Key messages
Global Development Challenges: The livestock dimensions

Promoting growth with equity—smallholder participation
Connecting smallholders to markets
Raising livestock productivity
Animal-human-ecosystems health and food safety
Rendering livestock systems more environmentally sustainable
Ameliorating the effects of climate change on livestock

ILRI PhotoBlog — ‘Livestock Still Lives’: Roof in Rajasthan

Posted on May 29, 2013 by Susan MacMillan

Stairs to the roof of a typical livestock-keeping household in the village of Nagar, in Tonk District, Rajasthan, India (photo credit: ILRI/Stevie Mann).

To receive alerts of new postings on this ILRI News Blog, including livestock-related images like the one above published in a series of ‘photoblogs’, please subscribe to the ILRI News Blog by clicking on one of the buttons in the righthand column of this page: ‘Subscribe by email’ or ‘Subscribe to newsfeed’. Thank you!

Dialing back on the drivers of global disease outbreaks: A look inside the ‘black box’

Posted on May 17, 2013 by Susan MacMillan

As published in PNAS 2013: 1208059110v1-201208059. Zoonosis emergence linked to agricultural intensification and environmental change, by Delia Grace and others, May 2013.

By Michelle Geis

A new report on the ‘causes of causes’ of H7N9 and other diseases that are emerging in animals and jumping species—into people

The deadly H7N9 bird flu virus in China and the spread of a SARS-like coronavirus in the Middle East continue to make headlines. H7N9 has killed 35 people in China and 20 have lost their lives to the novel coronavirus—which has spread from Saudi Arabia to the UK, France and Germany.

Two opinion editorials in the New York Times last week, The next contagion: Closer than you think and The next pandemic: Not if, but when, correctly warn us about the potential global spread of these killer diseases. They call for more awareness of the dangers of zoonotic (animal-to-people) diseases, faster identification of animal sources of the pathogens and better vaccines to protect us against them. All of those are indeed needed.

But like much of the mainstream press, neither article mentions the root cause of these emerging infectious diseases, that is, the conditions that make zoonoses likely to arise in the first place and then help turn them into lethal pandemics.

These ‘causes of causes‘ of zoonotic disease outbreaks and their spread are pinpointed in a paper published this week in the Proceedings of the National Academy of Sciences (PNAS). Delia Grace, a veterinary epidemiologist and food safety specialist at the International Livestock Research Institute (ILRI), in Nairobi, Kenya, and other scientists argue in this paper that we’ll only become capable of preventing or stopping the next pandemic when we better understand the drivers of disease emergence.

Some of these disease triggers are well-documented, if not well publicized. We know that rising demand for more meat and dairy products in rapidly growing developing countries, where cities and slums are densely crowded with livestock as well as people, can be a culprit. We know that animals kept in stressful as well as crowded conditions can be culprits. And we know that our expanding agriculture is fragmenting habitats, stressing wildlife and bringing people into contact with animals carrying pathogens, and reducing biodiversity, all of which encourage wildlife diseases to jump species.

A table published in the peer-reviewed article (see below) shows what conditions led to Ebola, HIV, SARS, Nipah, avian flu, Japanese encephalitis and more. Acknowledging and investigating these factors can provide governments and global health officials with important clues as to the next probable outbreak.

Table published in PNAS 2013: 1208059110v1-201208059. Zoonosis emergence linked to agricultural intensification and environmental change.

So, what is it that’s preventing us from anticipating and stopping the next global pandemic since we know the conditions likely to produce one? For one thing, as the paper discusses, the conditions that trigger diseases are changing more rapidly than the research that examines them.

Another challenge is that though an emerging disease event is reported somewhere in the world on average every four months, the likelihood of emergence in any given farm or farming system is low.

As Grace explains, ‘Taking action to slow the drivers of disease is good for humanity but not likely to have any observable benefits to the individual farmer. Hence, the society that benefits from less disease emergence must provide the incentives to dial back on the drivers.’

Finally, the world is increasingly farming on the margins, with most of the last few remaining near-pristine ecosystems now being invaded and destabilized. Just as inexorable is the move to rapidly growing cities of poor rural people, who are bringing their livestock with them. The resulting losses of biodiversity, and the rise of genetically improved, and thus similar, animal populations, also increases the risk of a pandemic emerging. Climate and environmental changes are generally making matters worse.

Grace says research must better examine the complex, context-specific, and interrelated nature of zoonotic pathogen emergence.

‘First’, she said, ‘we need to look inside the black box of the big trends driving disease emergence: urbanization, intensification, globalization, loss of habitat and biodiversity.

‘We also need to understand what causes matter most in different situations and which are amenable to mitigation.

‘And we need to develop ways of doing agriculture differently, ways that not only reduce disease emergence but also can be adopted at large scale.

‘Given that disease emergence is predictably unpredictable, much can be achieved by understanding, monitoring and managing pathogen dynamics before infectious agents emerge.’

Read the paper in Proceedings of the National Academy of Sciences: Zoonosis emergence linked to agricultural intensification and environmental change, by Bryony A Jones, Delia Grace, Richard Kock, Silvia Alonso, Jonathan Rushton, Mohammed Y Said, Declan McKeever, Florence Mutua, Jarrah Young, John McDermott and Dirk Udo Pfeiffer, PNAS 2013 : 1208059110v1-201208059.

Michelle Geis is a Washington DC-based science communications expert who works for Burness Communications.

ILRI’s global livestock research agenda: A strategy for ‘better lives through livestock’

Posted on May 15, 2013 by Susan MacMillan

Jimmy Smith, director general of ILRI, speaks about the past, present and future of ILRI at ILRI’s Annual Program Meeting 2013, in Addis Ababa, Ethiopia (photo credit: ILRI/Zerihun Sewunet).

Jimmy Smith, director general of the International Livestock Research Institute (ILRI), opened ILRI’s Annual Program Meeting today (15 May 2013), which is being held on ILRI’s campus in Addis Ababa, Ethiopia, with some 250 participants, with a quick review (especially for ILRI’s many new staff) of where the institute has come from, where it is now and where it’s going.

Here’s some of what he said.

Ever since the food crisis in 2007, issues around food security have dominated global discussions. At the same time, we began to see that our ability to increase food production using conventional methods is insufficient to feed the growing world population.

So it’s a great time for science. We have the attention of policymakers at the highest levels, who are depending on us to find ways to feed the world, to lift the world’s vast army of small-scale rural food producers out of poverty, and to protect our environments and their critical natural resources that are the foundation of agriculture and human well-being.

We have new opportunities to work across the developing world with our partners, including nongovernmental organizations and the broader development community, to translate this research into big development benefits.

It is this prospect that is buoying me up today.

Now, about where we’re going.

Where ILRI is going
From pathways out of poverty to better lives through livestock.
Smallholders can contribute to global food and nutritional security, and to broader development goals, and do so in ways that are sustainable.

From reactive responses to proactive management of livestock ‘bads’.
We’re not getting rid of cars but rather making them more efficient with new parts like this turbocharger for sale. Similarly, we’re not going to get rid of farm animals but we can and must make livestock production systems more efficient.

From regional presence to regional programs.
We will have a larger presence in the regions so that we can engage our regional partners in more meaningful ways.

From action research to development in action.
The new CGIAR requires that our work show impact—and we have to form the partnerships that will allow us to do that.

We’re removing our ‘candle from under the bushel’ so that we have influence.
Not a lot of people other than those who read agricultural papers in science journals know about ILRI. We must be able to speak to all, to be relevant to many different audiences. We must shine our candle everywhere livestock matters are important matters for the poor.

We’re restoring our biosciences lustre.
As funding for long-term research dried up in the 1980s and 90s, investments in agriculture, especially the more long-term agricultural research, declined precipitously. So we lost much of our ability to conduct upstream biological science in the critical fields of animal feeds, nutrition and health. We see an opportunity to regain ground and do advanced bioscience that complements our integrated animal science so that we deliver fully on our mandate.

We’re building a business culture.
We must deliver our products to agreed specifications and quality, within budget and on time.

We’re creating an enabling environment.
Your directors are not your masters but your servants; it’s our job to provide you with an enabling environment so you can do your jobs.

Last words
We must make ILRI the world’s renowned research for development institution.
To make a difference, we’ll have to be the difference, the preferred place people come to for pro-poor livestock science, products, information, technologies, policies . . . .

We must make ILRI the place to be and work.
We want every one of you to be profoundly satisfied with your work here.

We must work for the poor.
That’s what we signed up to. Not because it’s our job. Because it’s our mission.

View the whole slide presentation by Jimmy Smith.

Livestock, climate and poverty: A short history of work begun to unravel the complexity, and set useful priorities

Posted on May 13, 2013 by Susan MacMillan

Farming in eastern Africa (photo on Flickr by CIAT/Neil Palmer).

The story of human settlement and human evolution is very much tied to the fact that the earth’s climate has always been changing, and will continue to do so.

So begins a new brief developed by agricultural systems and climate change scientist Philip Thornton and his colleagues at the International Livestock Research Institute (ILRI), based in Nairobi, Kenya.

The brief goes on to say the following.

What is known about the likely impacts of climate change on resource-poor livestock keepers in the developing world? Relatively little, and the International Livestock Research Institute (ILRI) and the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS) are working to improve this knowledge.

‘This Brief outlines how a group of scientists at ILRI reviewed some elements of the complex relationship between livestock and climate change in developing countries with a forward-looking approach. The objective was to help set research priorities: to inform the debate as to what research for development organizations such as ILRI could and should be doing in the area of climate change work that could add value to the large amounts of work already being carried out by the Global Change community on cropping systems and natural resources management. . . .

Resource-poor livestock keepers: Mitigate and adapt
‘Changes in climate and climate variability will affect livestock production systems in all parts of the world, and will inevitably impact the 1.3 billion poor people whose livelihoods are wholly or partially dependent on livestock. At the same time, livestock production is a major contributor to greenhouse gas emissions.

Therefore, livestock keepers will have to mitigate emissions as well as adapt to change.

‘The adaptation and mitigation that are necessary may require significant changes in production technology and livestock production systems, which could affect productivity, incomes and livelihoods. Livestock production systems are highly heterogeneous, however, and different production systems have different capacities to adapt or to take on board the policy and regulatory changes that may be required in the future.

‘In developed countries, livestock systems are generally adaptable and resilient. In developing countries, in contrast, households that are dependent on livestock keeping may be much more vulnerable to changes in climate and climate variability, with the potential for increased poverty and decreased food security. At the same time, there may be considerable growth potential in the smallholder livestock sector, given projected increases in demand for livestock products globally and for biofuels and the land-use changes these may bring about. . . .

‘No formal evaluation has been undertaken, but this work certainly had some impact in addressing the lack of information on livestock in several integrated global assessments, despite livestock’s being recognized as one of the major drivers of global change. New partnerships have been forged with others working in the realm of global assessment. . . .

Way forward
‘[T]here is a need for improvement in the kind of indicators that are produced to gauge changes in social factors. Currently, impacts are usually expressed in terms of available calories and prices, for example, but there may be many other critical factors to assess future changes beyond food availability and commodity prices. Second . . . [is] the need to undertake priority-setting analyses on a regular basis, linked with other types of foresight and scenario processes . . . [and] explicitly linking priority setting with monitoring and evaluation, to provide more coordinated planning and implementation of research for development to improve its influence and to better demonstrate its value to the resource-poor of the developing world.’

Read the whole brief: Climate change: Do we know how it will affect smallholder livestock farmers? by Philip Thornton, Jeannette van de Steeg, An Notenbaert and Mario Herrero, a GFAR ‘The Futures of Agriculture’ Brief No. 43, May 2013.

This brief is based on two publications by ILRI scientists:
(1) Thornton P K, Notenbaert A, van de Steeg J and Herrero M, 2008, The livestock-climate-poverty nexus: A discussion paper on ILRI research in relation to climate change, published by ILRI, Nairobi, Kenya, 80 pp.

(2) Thornton P K, van de Steeg J, Notenbaert A and Herrero M, 2009. The impacts of climate change on livestock and livestock systems in developing countries: A review of what we know and what we need to know, Agricultural Systems 101: 113–127.

Note
This brief series was developed in preparation for the Foresight Breakout Session of the Global Conference on Agricultural Research for Development (GCARD 2012) and the Global Foresight Hub. The briefs were written to communicate to a wider audience, such as policy makers, civil society organizations, researchers, and funders.

ILRI PhotoBlog — ‘Livestock Portraits’: Sheko cattle in Ethiopia

Posted on May 10, 2013 by Susan MacMillan

Sheko calf kept in the Ghibe Valley of Southern Ethiopia (photo credit: Jim Richardson)

The above photo, taken by National Geographic photographer Jim Richardson, is of a Sheko calf kept in the Ghibe Valley of southern Ethiopia. The Sheko cattle breed is endangered, with only about 2,500 in existence today. They are a valuable breed because of their ability to resist diseases (African animal trypanosomiasis, related to human sleeping sickness) transmitted by Africa’s tsetse fly. The International Livestock Research Institute (ILRI) is protecting, studying, and breeding Sheko cattle in Ethiopia.

Read more here about ILRI’s work to conserve animal genetic resources of developing countries.

The livestock boom in India: Pathways to an increasingly profitable, pro-poor and sustainable sector

Posted on May 8, 2013 by Susan MacMillan

India, already the world’s biggest milk producer and beef exporter (mostly water buffalo), is investing in research to ensure that its poorest people reap increasing benefits from raising farm animals and do so in increasingly sustainable and healthy ways (photo credit: ILRI/Susan MacMillan).

Key recommendations from a high-level partnership dialogue held last November (2012) by the International Livestock Research Institute (ILRI) and the Indian Council for Agricultural Research (ICAR) have recently been published. These policy recommendations from ILRI and ICAR were released last week in New Delhi, India, by ILRI’s director general Jimmy Smith and ILRI’s deputy director general for integrated sciences John McIntire.

The ILRI-ICAR white paper distills major recommendations made at the partnership dialogue and serves as a basis for pro‐poor and sustainable livestock policy interventions in India.

The following excerpt is from the executive summary of this new publication.

‘With 485 million livestock plus 489 million poultry, India ranks first in global livestock population. Livestock keeping has always been an integral part of the socio‐economic and cultural fabric of rural India. In recent years, India’s livestock sector has been booming. Livestock now contribute about 25% of the output of the agricultural sector and the sub‐sector is growing at a rate of about 4.3% a year. With over 80% of livestock production being carried out by small‐scale and marginalized farmers, the benefits livestock generate for India’s poor are enormous and diverse.

‘Aimed to help cultivate joint learning, knowledge exchange and future partnership, the meeting brought together participants from 12 countries, including India. The attendance comprised of senior departmental heads in the government, directors of ICAR animal sciences national institutes, university vice chancellors, deans of veterinary universities, senior staff of leading non‐governmental organizations operating, representatives of farmer cooperatives, heads of private‐sector companies, and leaders and managers of international agencies including the Bill & Melinda Gates Foundation, the United Nations Food and Agriculture Organization (FAO) and the World Bank. All members of the ILRI Board of Trustees participated, as did officials of other CGIAR bodies operating in India.

‘The high‐level dialogue was inaugurated by Dr M.S. Swaminathan, renowned for his role in India’s Green Revolution of the 1960s and 70s. Dr Swaminathan stressed the urgent need for research and development partnerships to maintain sufficient momentum for the Indian livestock growth story. . . .

Dairy and small ruminant value chains
‘The gathered experts articulated the challenges and opportunities for the country’s millions of farmers trying to earn their living from small dairy and ruminant enterprises. What was critical was the consensus among experts in understanding that development of the country’s livestock value chains depends as much on smallholder access to services and inputs as it does on supply and marketing of livestock and their products. The participants also agreed that transforming India’s livestock value chains required better infrastructure and development of a policy framework for improved animal breeding.

Improved disease control
‘A subsequent session on animal health highlighted the need for better disease diagnostics, more affordable vaccines and better veterinary service delivery for small‐scale livestock keepers if the country was to succeed in better controlling diseases of livestock, as well as the many ‘zoonotic’ diseases that originate in farm animals and infect people as well. The experts in the session agreed that ICAR‐ILRI partnership should aim at capitalizing on ICAR’s excellent decision‐support system for predicting animal disease outbreaks in the country, and modify it further so as to make it highly valued and accessible for extensive use by scientists, administrators and policymakers alike.

Livestock nutrition
‘In another session presenting problems in animal nutrition, it was agreed that both conventional and new technologies should take ecological as well as economic considerations into account. With constant increase of animal numbers anticipated over the coming decades, fodder scarcities will have to be addressed through research work conducted to ensure the bio‐availability and digestibility of fodders available to India’s small‐scale livestock farmers.

‘All sessions of the all‐day dialogue named productive partnerships as crucial to bringing varied expertise together for designing sustainable solutions. In unison, the participants opinioned that such multi‐institutional and multi‐disciplinary expertise must understand that India’s animal expertise needs to ‘go to scale’ even as resources in fodder, land and water become ever more stretched.

‘Speakers and responders in the final session of the dialogue acknowledged the growing need of targeted research and development partnership in the country’s livestock sector. At the close of the day’s discussions, ILRI and ICAR signed a memorandum of understanding to help get research into use so as to accelerate the travel of research from laboratory to field, where it can transform lives of poor people.’

Download/read the publication: Livestock research and development summary report of the ICAR-ILRI Partnership Dialogue, 2013.

Read more about the Partnership Dialogue, 7 November 2012 on the ILRI News Blog:
India’s booming livestock sector: On the cusp?–Or on a knife edge?, 8 Nov 2013.

New advances in the battle against a major disease threat to cattle and people in Africa

Posted on May 1, 2013 by Susan MacMillan

An 8-month old cloned Boran calf named Tumaini (meaning ‘hope’ in Kiswahili), on the left, is part of a long-term ILRI research project to develop cattle for Africa that are genetically resistant to trypanosomiasis (photo credit: ILRI/Paul Karaimu).

The International Livestock Research Institute (ILRI), a member of the CGIAR Consortium, is a non-profit organization based in Africa. ILRI’s mission is to use the best and safest livestock science available to confront poverty, hunger, and disease in the developing world, where livestock provide livelihoods and food for hundreds of millions of people.

One of ILRI’s most important priorities today is to help poor livestock keepers in Africa deal with the constant threat of a devastating disease called trypanosomiasis. This disease is arguably Africa’s most important livestock disease, wasting and killing cattle, commonly the most important asset of poor households. The human form of the disease is called sleeping sickness, which afflicts tens of thousands of people every year, killing many of them, and putting tens of millions more people at risk.

As part of ILRI’s comprehensive fight against trypanosomiasis, the institute is now in the very early stages of a project to develop disease-resistant cattle, which could save the lives of livestock and people both. Thus far, ILRI and its partners have taken a preliminary step in the process, which involved successfully cloning a male calf from one of East Africa’s most important cattle breeds, the Boran. The calf is healthy and is being raised at ILRI’s research facilities in Kenya.

A next step is to develop a new Boran clone modified with a gene that naturally confers resistance to the disease. This involves using a synthetic copy of a gene sequence originally identified in baboons that should protect cattle against this devastating disease.

A final step will be to use these disease-resistant cattle in breeding schemes that will provide African countries with another option in their fight against trypanosomiasis.

This research potentially offers a reliable, self-sustaining and cost-effective way of protecting tens of millions of African cattle against disease and untimely death, as well as dramatically reducing poverty across Africa. By reducing the reservoir of pathogens, this should also help to save thousands of human lives each year.

It could take up to two decades to develop disease-resistant cattle herds for Africa. ILRI and its partners are also continuing to pursue other options for fighting trypanosomiasis, such as rationale drug treatment and integrated disease control methods.

For ILRI, public safety and animal welfare are paramount; this means working with all the relevant Kenyan and international regulatory authorities to ensure that the highest bio-safety standards are always employed. In line with its commitment to transparency, ILRI places all of its research results in the public domain.

ILRI is working with a team that includes scientists from New York University, along with experts from the Roslin Institute in Scotland, and Michigan State University in the USA. The fundamental research aspects of this project are being funded by the US National Science Foundation.

For further information, see:
ILRI website:
https://www.ilri.org/breadtrypanosome

National Science Foundation:
www.nsf.gov/news/news_summ.jsp?cntn_id=116932

2009 paper published in the Proceedings of the National Academy of Sciences (USA) on original breakthrough in this research project:
http://dx.doi.org/10.1073%2Fpnas.0905669106

Or contact one of the following people:

Jimmy Smith
ILRI Director General
j.smith@cgiar.org

Suzanne Bertrand
ILRI Deputy Director General for Biosciences
s.bertrand@cgiar.org

Steve Kemp
Leader of ILRI’s research on this topic
s.kemp@cgiar.org

About ILRI: better lives through livestock
www.ilri.org
The International Livestock Research Institute (ILRI) works with partners worldwide to enhance the roles that livestock play in food security and poverty alleviation, principally in Africa and Asia. The outcomes of these research partnerships help people in developing countries keep their farm animals alive and productive, increase and sustain their livestock and farm productivity, find profitable markets for their animal products, and reduce the risk of livestock-related diseases. ILRI is a not-for-profit institution with a staff of about 600 and, in 2012, an operating budget of about USD 60 million. A member of the CGIAR Consortium working for a food-secure future, ILRI has its headquarters in Nairobi, Kenya, a principal campus in Addis Ababa, Ethiopia, and offices in other countries in East, West and Southern Africa and in South, Southeast and East Asia.

About CGIAR: working for a food-secure future
www.cgiar.org
CGIAR is a global partnership that unites organizations engaged in research for a food-secure future. It is carried out by 15 centres that are members of the CGIAR Consortium and conducted in close collaboration with hundreds of partner organizations, including national and regional research institutes, civil society organizations, academia and the private sector. The CGIAR’s 8,000 scientists and staff work in the developing world to reduce rural poverty, increase food security, improve human health and nutrition, and ensure more sustainable management of natural resources. With unparalleled research infrastructure and dynamic networks across the globe, and maintaining the world’s most comprehensive collections of genetic resources, CGIAR is the only institution with a clear mandate on science and technology development for the eradication of hunger and poverty at the global level.

Alliance meeting this week to battle global ‘goat plague’

Posted on April 29, 2013 by Susan MacMillan

The PPR virus, commonly known as goat plague, swept across southern Ethiopia and northern Kenya in 2008; Mohammed Noor lost 20 goats in the just one week and wondered how he would provide for his family (photo on Flickr by EC/ECHO/Daniel Dickinson).

Assembling for two days this week (29–30 Apr 2013) in Nairobi, Kenya, are members of a global alliance against ‘peste des petits ruminants’, abbreviated as ‘PPR’ and also known as ‘goat plague’ and ‘ovine rinderpest’.

Co-hosting this second meeting of the Global Peste de Petits Ruminants (PPR) Research Alliance (hereafter referred to as GPRA) are the International Livestock Research Institute (ILRI), which is headquartered in Nairobi; the Biosciences eastern and central Africa-iLRI hub (BecA-ILRI Hub), hosted and managed by ILRI; the African Union-Interafrican Bureau for Animal Resources (AU-IBAR), also based in Nairobi; and the Australian Agency for International Development (AusAID).

Among the 70 or so people attending are representatives from the Bill & Melinda Gates Foundation (BMGF, Yi Cao), the Global Alliance for Livestock Veterinary Medicines (GALVMed, Bapti Dungu), the International Atomic Energy Agency (IAEA, Adama Diallo), the Pan African Veterinary Vaccine Centre (PANVAC), the Royal Veterinary College of the University of London Vet School (RVC), the United Nations Food and Agriculture Organization (FAO, Vincent Martin and Robert Allport, among others), the World Organisation for Animal Health (OIE, Jemi Domenech and Walter Masiga) and a range of national research institutions from developing countries where the disease is endemic.

What’s this alliance all about?
The GPRA is a participant-owned network of researchers and development professionals with an interest in the progressive control of PPR. The GPRA was inaugurated in 2012 at a meeting in London. GPRA aims to provide scientific and technical knowledge towards methods for the detection, control and eradication of PPR that are economically viable, socially practical and environmentally friendly.

Why, and how much, does PPR matter?
Infectious diseases remain the major limitation to livestock production globally and are a particular scourge in the developing world, where most of the world’s livestock are raised. Diseases not only kill farm animals but also cause production losses and hinder access to potentially high-value international livestock markets.

PPR, an infectious viral disease of sheep and goats, poses a major threat to the livelihoods of smallholder farmers in Africa as well as the Middle East and India. The disease is highly contagious, and has roughly an 80 per cent mortality rate in acute cases.

The impacts of PPR, which is closely related to rinderpest in cattle, have been expanding in recent years. At least 15 million sheep and goats are at risk of death from the disease in Kenya alone and the estimated economic impact of current PPR outbreaks—including production losses and disease control costs for Africa—is more than US$147 million per year. A recent outbreak of PPR in the Marakwet and Baringo districts of Kenya destroyed more than 2000 herds, with the disease spreading in days and farmers losing some KShs6 million (about US$70,000) to the disease over about three months.

PPR is probably the most important killer of small ruminant populations in affected areas and some 65 per cent of the global small ruminant population is at risk from PPR.

Increasing interest in tackling PPR
Over the last several years, international experts and national authorities have both been increasingly prioritizing the progressive control of PPR, with the first phase designed to contribute to the long-term goal of eradication. Donor interest in this research and development area quickly ramped up over the past year. A current AusAID-funded project being conducted under a partnership between the BecA-ILRI Hub and Australia’s Commonwealth Scientific, Industrial and Research Organisation (CSIRO) has supported development of a thermostable vaccine now being piloted in vaccination campaigns in Sudan and Uganda, with similar work proposed for Ethiopia.

Collins Owino, an ILRI research technician working on vaccines and diagnostics in the peste des petits ruminants (PPR) project (photo credit: ILRI/Evelyn Katingi).

Need for coordinated and progressive control of PPR
There is a growing recognition of the need for, and potential benefits of, a coordinated approach to the progressive control of PPR. The disease is now one of the high priorities of AU-IBAR, FAO and OIE, all of which have strong networks and expertise to offer the alliance. The role of the Global PPR Research Alliance as a network of research and development organizations is to develop a coordinated strategy to contribute to the progressive control of PPR.

The Australian Government, together with AU-IBAR and ILRI, is supporting the second meeting of the GPRA to advance with many other stakeholders progressive global control of PPR, particularly through collaborative research. The GPRA supports the sharing of relevant information and results, the establishment of productive working relationships among stakeholders, the establishment of research and development projects of interest to some or all members, and the closer linking of strategic plans of all stakeholders in better control of this disease.

Is progressive eradication of PPR possible?
Wide calls for PPR’s progressive global eradication cite the following factors supporting this goal:

The close relationship of PPR/’goat plague’ with the recently eradicated ‘cattle plague’ known as ‘rinderpest’ (rinderpest was only the second infectious disease, and the first veterinary disease, to be eradicated from the globe)
The availability of effective vaccines against PPR
The development of heat-stable PPR vaccines, following the same procedures that were so effective in developing a heat-stable rinderpest vaccine
The opportunity to increase focus on Africa and Asia’s small ruminants, which are of critical importance to the livelihoods of rural smallholder and pastoralist communities in many of the world’s poorest countries
The existence of vaccines and diagnostics considered sufficient to initiate the program; the current vaccines (based on the strain Nigeria 75/1) are safe, efficacious and provide life-long immunity.

More about the AusAID-funded PPR project at the BecA-ILRI Hub
The Australian Government via AusAID has funded development at ILRI of thermostable formulations of the PPR vaccine that provide a level of stability in the field as high as that demonstrated in the vaccine used to eradicate rinderpest. The project team has demonstrated that the PPR vaccine can be stored without refrigeration for extended periods of time without significant loss in viability. This is a crucial and significant success. Under the guidance of ILRI senior scientist Jeff Mariner and with the assistance of Australia’s CSIRO and BecA-ILRI Hub staff, the project team have developed strong links with AU-IBAR’s Henry Wamwayi, a senior member of his organization seconded to the PPR project.

ILRI veterinary epidemiologist Jeff Mariner presenting lessons learned from work to eradicate rinderpest at a meeting of the World Animal Health Organisation (OIE) (photo credit: OIE).

Next steps
The project has built on lessons learned from the recent global eradication of rinderpest, which depended on two equally important breakthroughs for its success: development of an effective thermostable vaccine and effective vaccine delivery networks in remote as well as other regions. The next 12 months of the PPR research project will focus on testing the vaccine and delivery strategies in South Sudan and Uganda. Staff will assess in the field just how effective the vaccine is in controlling PPR infections. They’ll also investigate some practical incentives for encouraging livestock owners and livestock service delivery personnel to participation in PPR control programs. And they’ll look into ways to build and enhance public-private community partnerships to deliver the PPR vaccine.

Read more in the ILRI News Blog and science journals about the close connections between the eradication of rinderpest and this new battle against PPR—and the role of ILRI’s Jeff Mariner in development of thermostable vaccines necessary to win the battle against both diseases.

Rinderpest: Scourge of pastoralists defeated, at long last, by pastoralists, 18 Sep 2012.

New analysis in ‘Science’ tells how the world eradicated deadliest cattle plague from the face of the earth, 13 Sep 2012.

Goat plague next target of veterinary authorities now that cattle plague has been eradicated, 4 Jul 2011.

Deadly rinderpest virus today declared eradicated from the earth—’greatest achievement in veterinary medicine’, 28 Jun 2011.

As a new round of bird flu hits China, livestock scientist advises to ‘panic slowly’

Posted on April 15, 2013 by Susan MacMillan

At the chicken market in Xining, Lanzhou Province, China (photo on Flickr by Padmanaba01).

By Matthew Davis

The initial news reports were slim on details but the reaction was swift. There were at least three people dead in China after apparently contracting influenza from birds. Prices of soybean—a major ingredient in livestock feed—immediately took a dive.

Then the death toll rose to five, virus samples were detected in pigeons, and in Shanghai authorities began slaughtering poultry flocks. Within a few days the death count was up to seven, then nine. And people started to wonder about a connection to all those pig carcasses floating down Shanghai waterways.

Such is the confusing swirl of information emanating from the latest incident in which a worrisome disease has passed from animal to human, a phenomena—and a quite common one at that—known as zoonoses. In this instance, it’s an influenza virus called H7N9 that appears to have originated in wild or domestic bird populations, but much about its source remains murky.

For Delia Grace, a veterinary epidemiologist at the International Livestock Research Institute (ILRI) who spends most of her waking hours studying zoonotic events around the world, there are two essential facts to keep in mind as the situation in China evolves. And they embody how difficult it can be to craft a proper response.

One: the vast majority of zoonoses outbreaks do not escalate to crisis proportions. But, two: every now and then, as happened with Spanish flu in 1918 and AIDS in more recent times, an animal disease jumps to human hosts and causes a ‘civilization altering event’.

Grace suggests the appropriate reaction is to ‘panic slowly’. In other words, be prepared to move quickly if things get worse, but don’t over-react to the early reports. Also, keep in mind that, just based on what gets reported, a new disease emerges somewhere in the world about every four months.

For example, Grace noted that epidemiologists in the United Kingdom, Germany, and the Middle East are probably more concerned right now about a new and deadly corona virus that as of late March had killed 11 of the 17 people known to have been infected. There is evidence that at least one of the infections may have originated in racing camels.

Grace advises decision-makers in the public and private sector to channel the impulse to take action toward addressing conditions that are intensifying zoonotic threats.

We know that in certain parts of the world, livestock intensification is being pushed well beyond the limits of anything we have done in agriculture in the past’, she said. ‘There are hundreds of thousands of animals packed together and little transparency about how they are being managed. And that’s making disease experts pretty nervous.’

But Grace cautions against focusing solely on the risks posed by certain livestock practices and ignoring the fact that livestock are a major source of food and income for 1 billion of the world’s poorest people. She worries that misguided reactions to emerging zoonotic diseases can end up doing significant harm to their lives and livelihoods.

For example, in 2009, the Egyptian government ordered the mass slaughter of pigs tended by Coptic Christians on the mistaken belief that the pigs were linked to the H1N1 flu pandemic. Also, the possible link in Asia between a different, and also deadly, form of avian influenza called H5N1 and ‘backyard’ poultry farming has prompted a shift to more industrial-scale production. Yet, as Grace points out, given the problems plaguing industrial operations in the region, this shift could actually increase the risk of zoonotic diseases while imperiling the food security of livestock keepers.

‘The proper reaction to the risks posed by emerging zoonotic diseases is not to indiscriminately slaughter animals. That could threaten the health of far more people by depriving them of their primary source of protein and other nutrients’, Grace said.

What we need to do is look at the many ways livestock production has gone wrong—lack of diversity in animals, using drugs to mask signs of diseases, dirty conditions—and put them to right.

Matthew Davis is a Washington DC-based science writer and policy analyst; he also serves as a senior consulting writer for Burness Communications.

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